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[中国徐州地区成人血液学参数参考区间的调查与建立]

[Survey and Establishment of the Hematological Parameter Reference Intervals for Adult in Xuzhou Area of China].

作者信息

Zhang Xiao-Tian, Qi Kun-Ming, Cao Jiang, Xu Kai-Lin, Cheng Hai

机构信息

Institute of Hematology, Xuzhou Medical, University, Xuzhou 221002,Jiangsu Province, China.

Institute of Hematology, Xuzhou Medical, University, , Xuzhou 221002,Jiangsu Province, China,Department of Hematology,The Affiliated Hospital of Xuzhou Medical University, Xuzhou 221002, Jiangsu Province, China.

出版信息

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Apr;27(2):549-556. doi: 10.19746/j.cnki.issn.1009-2137.2019.02.039.

Abstract

OBJECTIVE

To establish the reference intervals of the hematological parameters in normal adult people of Xuzhou erea.

METHODS

The red blood cells (RBC), platelets, white blood cells (WBC) and related parameters were detected by hematoanalyzers in 82514 healthy people including 41257 males and 41257 females in the Medical Center of the Affiliated Hospital of Xuzhou Medical University.

RESULTS

The range of RBC count: (4.33-5.51) ×10/L in male and(3.82-4.85)×10/L in female, the range of Hb level: (132-172) g/L in male and(107-145)g/L in female, the range of HCT: 40 %-50 % in male and 34 %-44 % in female, the range of platelet count: (113-268) ×10/L in male and (126-289) ×10/L in female, the range of WBC count: (4.00-9.40) ×10/L in male and (3.54-9.30)×10/L in female, the range of NEUT count: (1.91-5.76) ×10/L in male and(1.67-5.30)×10/L in female, the range of MONO count: (0.18-0.58) ×10/L in male and(0.16-0.52)×10/L in female, the range of LYM is(1.3-3.4)×10/L in male and(1.2-3.1)×10/L in female, etc.Conclusion: There is significant difference in the blood cell parameters between Xuzhou and other areas. Among them, the lower limit of Hb reference interval for adult women in Xuzhou area is obviously lower, and the upper and lower limits of adult Plt reference interval are significantly lower than other areas in China and abroad. The upper and lower limits of the WBC reference interval are close to the domestic areas, but lower than that in some foreign regions. Through this survey, the reference intervals of different hematologic parameters of healthy people in Xuzhou area primarily has been established, Some of the indexes, such as RBC, Hb, HCT, and Plt have significant sex differences. The reference intervals for them have been estublisted respectively.

摘要

目的

建立徐州地区正常成年人血液学参数的参考区间。

方法

采用血液分析仪检测徐州医科大学附属医院医学中心82514例健康人(男性41257例,女性41257例)的红细胞(RBC)、血小板、白细胞(WBC)及相关参数。

结果

男性RBC计数范围为(4.33 - 5.51)×10¹²/L,女性为(3.82 - 4.85)×10¹²/L;男性Hb水平范围为(132 - 172)g/L,女性为(107 - 145)g/L;男性HCT范围为40% - 50%,女性为34% - 44%;男性血小板计数范围为(113 - 268)×10⁹/L,女性为(126 - 289)×10⁹/L;男性WBC计数范围为(4.00 - 9.40)×10⁹/L,女性为(3.54 - 9.30)×10⁹/L;男性NEUT计数范围为(1.91 - 5.76)×10⁹/L,女性为(1.67 - 5.30)×10⁹/L;男性MONO计数范围为(0.18 - 0.58)×10⁹/L,女性为(0.16 - 0.52)×10⁹/L;男性LYM范围为(1.3 - 3.4)×10⁹/L,女性为(1.2 - 3.1)×10⁹/L等。结论:徐州地区与其他地区血细胞参数存在显著差异。其中,徐州地区成年女性Hb参考区间下限明显较低,成年Plt参考区间上下限均显著低于国内外其他地区。WBC参考区间上下限与国内地区相近,但低于部分国外地区。通过本次调查,初步建立了徐州地区健康人不同血液学参数的参考区间,部分指标如RBC、Hb、HCT、Plt存在显著性别差异,已分别建立其参考区间。

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