Pediatric Urodynamic Centre, Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Department of Urology, Shenzhen Children's Hospital, Shenzhen, China.
Neurourol Urodyn. 2019 Jun;38(5):1423-1429. doi: 10.1002/nau.24002. Epub 2019 Apr 18.
A pilot survey shows that primary nocturnal enuresis (PNE) prevalence has increased significantly during the past decade in Mainland China. Whether it is related to the delay of elimination communication (EC) is unclear. This study retrospectively investigated the influence of delayed EC on the PNE prevalence in children and adolescents in mainland China.
A cross-sectional study of PNE prevalence was performed by distributing 19 500 anonymous self-administered questionnaires to parents in five provinces of mainland China from July 2017 to October 2017. The questionnaires included sociodemographic data, family caregivers' information, and details about the disposable diapers (DD) usage, EC commencement date, psychological disorders, lower urinary tract symptoms, and family history of PNE in children and adolescents. The 2017 PNE prevalence was compared with that of 2006 in Mainland China.
The total response rate was 97.04% (18 631 of 19 500) and 92.39% (18 016 of 19 500) qualified for statistical analysis. The PNE prevalence in 2017 has increased significantly compared to that of 2006 (7.30% vs 4.07%, P < 0.001). The PNE prevalence in children with EC starting before 6 months of age was significantly lower than those who start after 12 months of age. The longer DD were used and the later the beginning of EC, the higher the PNE prevalence was found.
The PNE prevalence in Mainland China has increased significantly during the past 10 years. A longer use of DD and later onset of EC may be risk factors for PNE.
一项初步调查显示,过去十年中国大陆儿童原发性夜间遗尿症(PNE)的患病率显著增加。其是否与排泄性沟通(EC)延迟有关尚不清楚。本研究回顾性调查了中国大陆儿童和青少年延迟 EC 对 PNE 患病率的影响。
2017 年 7 月至 10 月,通过向中国大陆五个省份的家长分发 19500 份匿名自填问卷,进行 PNE 患病率的横断面研究。问卷包括社会人口统计学数据、家庭照顾者信息,以及儿童和青少年一次性尿布(DD)使用、EC 开始日期、心理障碍、下尿路症状和 PNE 家族史的详细信息。将 2017 年 PNE 患病率与 2006 年中国大陆进行比较。
总回复率为 97.04%(19500 份中的 18631 份),92.39%(19500 份中的 18016 份)符合统计分析要求。与 2006 年相比,2017 年 PNE 患病率显著增加(7.30%比 4.07%,P<0.001)。EC 开始于 6 个月龄之前的儿童 PNE 患病率明显低于 12 个月龄之后开始的儿童。DD 使用时间越长,EC 开始时间越晚,PNE 患病率越高。
过去 10 年中国大陆 PNE 患病率显著增加。DD 使用时间延长和 EC 开始时间延迟可能是 PNE 的危险因素。