1 Department of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland.
2 Department of Electrical and Computer Engineering, Bethlehem, Pennsylvania.
Tissue Eng Part C Methods. 2019 Jun;25(6):334-343. doi: 10.1089/ten.TEC.2018.0318.
This article describes a method for the biofabrication of skin tissue equivalents in a multiwell plate format. The technique and results overcome shortcomings of previously published engineering methods, and show good architecture and barrier function from well to well; thus it may be used for compound functional testing and for the development of disease tissue models for screening.
本文描述了一种在多孔板中制造皮肤组织等效物的生物制造方法。该技术和结果克服了先前发表的工程方法的缺点，并且在孔与孔之间显示出良好的结构和屏障功能；因此，它可用于化合物功能测试和用于筛选的疾病组织模型的开发。
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