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基于主动流控的扭转超声乳化术在糖尿病眼中的应用:一项前瞻性介入研究。

Active-fluidics-based torsional phacoemulsification in diabetic eyes: A prospective interventional study.

机构信息

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Ophthalmol. 2019 May;67(5):619-624. doi: 10.4103/ijo.IJO_1146_18.

Abstract

PURPOSE

To compare the outcomes of active-fluidics based torsional phacoemulsification in diabetics and nondiabetics using a balanced tip.

METHODS

Two hundred and forty-eight patients undergoing senile cataract surgery using torsional phacoemulsification on an active-fluidics-based platform from December 2016 to August 2017 were included in this prospective, nonrandomized, interventional cohort study; of the 248 patients, 54 were controlled diabetics and 194 were nondiabetics. Intraoperative parameters such as cumulative dissipated energy (CDE), total ultrasound time, torsion usage time, torsion amplitude, aspiration time, and fluid usage were documented and compared. Endothelial cell loss (ECL) and central corneal thickness (CCT) were evaluated at 1 month postoperatively.

RESULTS

Diabetics and nondiabetics did not differ in CDE, total ultrasound time, torsion amplitude, aspiration time, fluid usage, endothelial cell count, and CCT. ECL on Day 1 (10.2 ± 8.0%) and Day 30 (11.05 ± 8.3%) were significantly higher in diabetics (P = 0.025 and P = 0.045, respectively). There was an increase in CCT on Day 1 (P = 0.018), which settled by Day 30. Grade 4 cataracts in diabetics had significantly higher CCT at Day 1 (P = 0.032) and Day 30 (P = 0.007). In the diabetic subgroup, Grades 3 and 4 cataracts required lower CDE (P < 0.001) and Grade 4 cataracts showed higher ECL than others till 1 month of follow-up (P < 0.05).

CONCLUSION

Intraoperative and postoperative parameters after torsional phacoemulsification are comparable in diabetics and nondiabetics. Endothelial changes and pachymetry may be related to the grade of cataract in diabetics.

摘要

目的

比较基于主动射流的扭动力超声乳化术在糖尿病患者和非糖尿病患者中的效果,使用平衡尖端。

方法

本前瞻性、非随机、干预性队列研究纳入了 2016 年 12 月至 2017 年 8 月期间在基于主动射流的平台上接受扭动力超声乳化术治疗的 248 例老年白内障患者;其中 54 例为控制良好的糖尿病患者,194 例为非糖尿病患者。记录并比较术中参数,如累积耗散能量(CDE)、总超声时间、扭转使用时间、扭转幅度、抽吸时间和液体使用量。术后 1 个月评估内皮细胞丢失(ECL)和中央角膜厚度(CCT)。

结果

糖尿病患者和非糖尿病患者的 CDE、总超声时间、扭转幅度、抽吸时间、液体使用量、内皮细胞计数和 CCT 无差异。糖尿病患者第 1 天(10.2±8.0%)和第 30 天(11.05±8.3%)的 ECL 明显更高(P=0.025 和 P=0.045)。第 1 天(P=0.018)和第 30 天(P=0.045)CCT 升高,第 30 天恢复正常。糖尿病患者 4 级白内障在第 1 天(P=0.032)和第 30 天(P=0.007)时 CCT 明显更高。在糖尿病亚组中,3 级和 4 级白内障需要更低的 CDE(P<0.001),而 4 级白内障在术后 1 个月的 ECL 高于其他组别(P<0.05)。

结论

在糖尿病患者和非糖尿病患者中,扭动力超声乳化术后的术中及术后参数相似。内皮改变和角膜厚度可能与糖尿病患者的白内障分级有关。

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