Katchy Amechi Uchenna, Eyesan Samuel Uwale, Awotunde Timothy Olufemi, Adesina Stephen Adesope, Ayandele Babajide Oladayo, Sabageh Donatus
Department of Orthopaedic Surgery, University of Nigeria Teaching Hospital, Nsukka, Nigeria.
Department of Orthopaedic Surgery, Bowen University Teaching Hospital, Ogbomosho, Nigeria.
J Res Med Sci. 2019 Mar 25;24:19. doi: 10.4103/jrms.JRMS_97_18. eCollection 2019.
Histoplasmosis due to is an emerging AIDS-defining opportunistic infection in HIV positive seen predominantly on the African continent between the Tropics of Cancer and Capricorn. is an invasive fungal organism with tropism for lymph nodes, skin and bones. The infection occurs more in patients with a CD4 count <50/mm and is usually dissemnnated Histoplasmosis due to is an emerging AIDS-defining opportunistic infection in HIV positive seen predominantly on the African continent between the Tropics of Cancer and Capricorn. is an invasive fungal organism with tropism for lymph nodes, skin and bones. The infection occurs more in patients with a CD4 count <50/mm and is usually disseminated. Literature reports of its occurrence in HIV negative patients are scanty. We report a case of histoplasma dubiosii infection of the left femur in a 9 year old HIV negative Nigerian with swelling in the left thigh of 5 months duration. Oral antibiotics and analgesics were prescribed for the patient with satisfactory clinical outcome. To our knowledge, this is the first reported case in an immunocompetent child in Nigeria. Literature reports of its occurrence in HIV negative patients are scanty. We report a case of histoplasma dubiosii infection of the left femur in a 9 year old HIV negative Nigerian with swelling in the left thigh of 5 months duration. Oral antibiotics and analgesics were prescribed for the patient with satisfactory clinical outcome. To our knowledge, this is the first reported case in an immunocompetent child in Nigeria.
由[未提及具体名称]引起的组织胞浆菌病是一种在HIV阳性患者中出现的、主要在非洲大陆南北回归线之间可见的、可定义艾滋病的机会性感染。[未提及具体名称]是一种侵袭性真菌病原体,对淋巴结、皮肤和骨骼具有嗜性。该感染在CD4细胞计数<50/mm的患者中更为常见,且通常为播散性。关于其在HIV阴性患者中发生的文献报道很少。我们报告一例9岁HIV阴性尼日利亚儿童左股骨杜波伊斯组织胞浆菌感染病例,左大腿肿胀持续5个月。为该患者开具了口服抗生素和镇痛药,临床结果令人满意。据我们所知,这是尼日利亚免疫功能正常儿童中首例报告病例。关于其在HIV阴性患者中发生的文献报道很少。我们报告一例9岁HIV阴性尼日利亚儿童左股骨杜波伊斯组织胞浆菌感染病例,左大腿肿胀持续5个月。为该患者开具了口服抗生素和镇痛药,临床结果令人满意。据我们所知,这是尼日利亚免疫功能正常儿童中首例报告病例。