Genome sequencing and characterization of three Bacillus cereus-specific phages, DK1, DK2, and DK3.
作者信息
Kong Li, Ding Yu, Wu Qingping, Wang Juan, Zhang Jumei, Li Hongye, Yu Shubo, Yu Pengfei, Gao Tiantian, Zeng Haiyan, Yang Meiyan, Liang Yongjian, Wang Zhi, Xie Zhiqing, Wang Qianwen
机构信息
Department of Food Science & Technology, Jinan University, Huangpu Ave. 601, Guangzhou, 510632, China.
Institute of Microbiology, State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Xianlie Zhong Road 100 #, 58th Building, Guangzhou, 510070, China.
出版信息
Arch Virol. 2019 Jul;164(7):1927-1929. doi: 10.1007/s00705-019-04258-1. Epub 2019 Apr 22.
In the study, three Bacillus cereus-specific phages, named DK1, DK2 and DK3, belonging to the family Podoviridae, were isolated from Pearl River water and sludge in Guangzhou, China. The genomes of DK1, DK2 and DK3 were 27,180 bp, 26,357 bp, and 26,865 bp in length and contained 49, 45 and 46 open reading frames, respectively. Among the three phages, DK2 shared the highest genome sequence similarity (96% identity) with DK3. Genes encoding rRNA, tRNA, virulence factors and antibiotic resistance were absent in these phage genomes. In addition, comparative genomic and phylogenetic analysis revealed that they were novel phages of B. cereus. Each genome encoded a putative endolysin that might be of value for the control of the foodborne pathogen B. cereus.
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