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曲安奈德皮损内注射导致的线性额部皮损,并用透明质酸填充物治疗:病例报告。

A linear forehead lesion caused by intralesional injection of triamcinolone acetonide and treated with hyaluronic acid filler: Case report.

机构信息

Department of Dermatology, University of Rome Tor Vergata, Rome, Italy.

出版信息

Dermatol Ther. 2020 Nov;33(6):e14526. doi: 10.1111/dth.14526. Epub 2020 Nov 20.

DOI:10.1111/dth.14526
PMID:33174645
Abstract

Intralesional steroid injection is a treatment method frequently used to resolve a large number of orthopedic, rheumatological, dermatological, and neurological disorders. Although this treatment is very effective, it is not without possible side effects, both systemic and local, among which we can mention pain, bleeding, ulceration, atrophy, pigmentary changes, calcification, secondary infections, formation of granulomas, allergic reactions and, in very rare cases, the development of linear atrophy, and hypopigmentation. Here, we present a case of frontal linear skin atrophy after intralesional steroid injection for the treatment of alopecia areata (AA) in a 29 year-old patient, successfully treated with a hyaluronic acid filler.

摘要

病灶内类固醇注射是一种常用于解决大量骨科、风湿科、皮肤科和神经科疾病的治疗方法。尽管这种治疗非常有效,但并非没有可能的副作用,包括全身和局部的副作用,其中我们可以提到疼痛、出血、溃疡、萎缩、色素改变、钙化、继发感染、肉芽肿形成、过敏反应,在极少数情况下,还会出现线性萎缩和色素减退。在这里,我们报告了一例 29 岁患者因斑秃(AA)接受病灶内类固醇注射治疗后出现额部线性皮肤萎缩的病例,使用透明质酸填充物成功治疗。

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1
A linear forehead lesion caused by intralesional injection of triamcinolone acetonide and treated with hyaluronic acid filler: Case report.曲安奈德皮损内注射导致的线性额部皮损,并用透明质酸填充物治疗:病例报告。
Dermatol Ther. 2020 Nov;33(6):e14526. doi: 10.1111/dth.14526. Epub 2020 Nov 20.
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Intralesional pentoxifylline injection in localized alopecia areata.局部注射己酮可可碱治疗局限性斑秃
J Cosmet Dermatol. 2019 Apr;18(2):602-607. doi: 10.1111/jocd.12796. Epub 2018 Oct 9.
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Treatment of severe alopecia areata with intralesional steroid injections.皮损内注射类固醇治疗重度斑秃。
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Intralesional corticosteroid-induced hypopigmentation and atrophy.皮损内注射皮质类固醇激素引起的色素减退和萎缩。
Dermatol Online J. 2020 Jan 15;26(1):13030/qt0bj81707.
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Efficacy of different concentrations of intralesional triamcinolone acetonide for alopecia areata: A systematic review and meta-analysis.不同浓度曲安奈德皮损内注射治疗斑秃的疗效:一项系统评价和荟萃分析
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Intraocular Pressure Increases After Intraarticular Knee Injection With Triamcinolone but Not Hyaluronic Acid.关节内注射曲安奈德会导致眼内压升高,但注射透明质酸不会。
Clin Orthop Relat Res. 2018 Jul;476(7):1420-1425. doi: 10.1007/s11999.0000000000000261.
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Linear cutaneous hypopigmentation and atrophy associated with intralesional steroid injection: A rarely described adverse reaction.线性皮肤色素减退伴萎缩与皮损内类固醇注射相关:一种罕见的不良反应。
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Hyperglycemia following intralesional corticosteroid injection in a patient with type I diabetes mellitus.1 型糖尿病患者行皮损内皮质类固醇注射后发生高血糖症。
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Intralesional betamethasone triamcinolone acetonide in the treatment of localized alopecia areata: a within-patient randomized controlled trial.局部注射曲安奈德治疗斑秃:一项自身对照随机临床试验。
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Subacromial triamcinolone acetonide, hyaluronic acid and saline injections for shoulder pain an RCT investigating the effectiveness in the first days.肩峰下注射曲安奈德、透明质酸和生理盐水治疗肩部疼痛:一项关于首日疗效的随机对照试验
BMC Musculoskelet Disord. 2014 Oct 23;15:352. doi: 10.1186/1471-2474-15-352.

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Treatment of Delayed Hypersensitivity After Injection of Nasal Fillers.注射鼻用填充剂后迟发型超敏反应的治疗。
J Cosmet Dermatol. 2025 Feb;24(2):e16681. doi: 10.1111/jocd.16681. Epub 2024 Dec 8.
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Unveiling the Hidden Dangers: Massive Allergic Dermatitis After Hyaluronic Acid Injection.揭示潜在风险:透明质酸注射后出现大面积过敏性皮炎
Clin Cosmet Investig Dermatol. 2024 Sep 23;17:2117-2121. doi: 10.2147/CCID.S477847. eCollection 2024.
3
Alopecia Areata: Current Treatments and New Directions.斑秃:现有治疗方法和新方向。
Am J Clin Dermatol. 2023 Nov;24(6):895-912. doi: 10.1007/s40257-023-00808-1. Epub 2023 Aug 22.