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用于筛查轻度认知障碍的两种中文版蒙特利尔认知评估量表的比较研究

Comparative study of two Chinese versions of Montreal Cognitive Assessment for Screening of Mild Cognitive Impairment.

作者信息

Huang Yu-Yuan, Qian Shu-Xia, Guan Qiao-Bing, Chen Ke-Liang, Zhao Qian-Hua, Lu Jia-Hong, Guo Qi-Hao

机构信息

Department of Neurology and Institute of Neurology, Huashan Hospital, Fudan University, Shanghai, China.

Department of Neurology, The Second Affiliated Hospital of Jiaxing College, Jiaxing, China.

出版信息

Appl Neuropsychol Adult. 2021 Jan-Feb;28(1):88-93. doi: 10.1080/23279095.2019.1602530. Epub 2019 Apr 23.

Abstract

Our aim was to compare the utility and accuracy of the Chinese Version of Montreal Cognitive Assessment Basic (MoCA-BC) and the Montreal Cognitive Assessment-Beijing Version (MoCA-BJ) in the identification of mild cognitive impairment (MCI) under different education levels. A sample of individuals with MCI ( = 295), Alzheimer's disease (AD;  = 254), and normal controls (NC;  = 259) at 2 Memory Clinics and communities was administered the MoCA-BC, MoCA-BJ, Mini-Mental State Examination (MMSE), and other neuropsychological tests. The discriminant validity of the MoCA-BC and MoCA-BJ as diagnostic instruments was ascertained. The overall discriminant validity for detection of MCI from NC (receiver operating characteristic area under the curve [95% confidence interval]) was that the MoCA-BC (0.95 [0.93, 0.97]) had better sensitivity and accuracy than MoCA-BJ (0.87 [0.84, 0.90]). In addition, we provide an easy to use table that enables the conversion of MoCA-BC to the MoCA-BJ scores or to MMSE scores. The MoCA-BC and MoCA-BJ provided good diagnostic accuracy when compared to MMSE. The MoCA-BC, which was proved to be an appropriate tool when screening for MCI among elderly subjects, can now be compared directly with the MoCA-BJ.

摘要

我们的目的是比较中文版蒙特利尔认知评估基础版(MoCA-BC)和蒙特利尔认知评估北京版(MoCA-BJ)在不同教育水平下识别轻度认知障碍(MCI)的效用和准确性。对2家记忆诊所和社区中的295例MCI患者、254例阿尔茨海默病(AD)患者以及259例正常对照(NC)进行了MoCA-BC、MoCA-BJ、简易精神状态检查表(MMSE)及其他神经心理学测试。确定了MoCA-BC和MoCA-BJ作为诊断工具的判别效度。从NC中检测MCI的总体判别效度(曲线下面积的受试者操作特征[95%置信区间])为,MoCA-BC(0.95[0.93,0.97])比MoCA-BJ(0.87[0.84,0.90])具有更好的敏感性和准确性。此外,我们提供了一个易于使用的表格,可将MoCA-BC分数转换为MoCA-BJ分数或MMSE分数。与MMSE相比,MoCA-BC和MoCA-BJ具有良好的诊断准确性。MoCA-BC在筛查老年受试者的MCI时被证明是一种合适的工具,现在可以直接与MoCA-BJ进行比较。

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