Abou Elez Rasha M M, Hassanen Eman A A, Tolba Hala M N, Elsohaby Ibrahim
Department of Zoonoses, Faculty of Veterinary Medicine, Zagazig University, Zagazig City 44511, Egypt.
Department of Parasitology, Faculty of Veterinary Medicine, Zagazig University, Zagazig City 44511, Egypt.
Vet Parasitol Reg Stud Reports. 2017 May;8:133-137. doi: 10.1016/j.vprsr.2017.02.009. Epub 2017 Mar 18.
A cross-sectional study was conducted from September 2014 to December 2015 to determine seroprevalence and potential risk factors associated with Toxoplasma gondii (T. gondii) infection in domestic rabbits and humans in Egypt. In total 290 blood samples were collected from humans (n=140) and slaughtered rabbits (n=150) and were analyzed using ELISA for T. gondii IgM and IgG antibodies. T. gondii IgM and IgG antibodies were detected in, respectively, 9 (6%) and 40 (26.7%) of 150 rabbits raised in Cairo, Qalyubia, and Sharkia Governorates, Egypt. Corresponding overall seroprevalences for human participants were 5.7% and 35.7%, respectively. Rabbit age, management (farm, backyard and pet shop) and the presence of cats at rabbit raising areas were significantly associated with the seroprevalence of T. gondii IgG antibodies. T. gondii IgG antibodies seropositivity in pregnant participants and rabbit butchers were 0.17 and 0.63 times lower than immunocompromised participants, respectively. However, participants who consumed undercooked rabbit meat was 7.59 times higher than participants who consumed meat from other sources. The results indicate that domestic rabbits are a potential source of T. gondii infections in human in Egypt. Thus, dissemination of protective measures is essential, especially for rabbit butchers and immunocompromised individuals.
2014年9月至2015年12月开展了一项横断面研究，以确定埃及家兔和人类中弓形虫感染的血清阳性率及相关潜在风险因素。共采集了290份血液样本，其中人类样本140份，屠宰家兔样本150份，并采用酶联免疫吸附测定法（ELISA）分析弓形虫IgM和IgG抗体。在埃及开罗、盖勒尤卜和谢赫村省饲养的150只家兔中，分别有9只（6%）和40只（26.7%）检测出弓形虫IgM和IgG抗体。人类参与者相应的总体血清阳性率分别为5.7%和35.7%。家兔年龄、饲养方式（农场、后院和宠物店）以及养兔地区是否有猫与弓形虫IgG抗体血清阳性率显著相关。孕妇参与者和家兔屠宰者的弓形虫IgG抗体血清阳性率分别比免疫功能低下参与者低0.17倍和0.63倍。然而，食用未煮熟兔肉的参与者比食用其他来源肉类的参与者高出7.59倍。结果表明，家兔是埃及人类弓形虫感染的一个潜在来源。因此，传播保护措施至关重要，特别是对家兔屠宰者和免疫功能低下的个体。
