Capino Amanda C, Johnson Peter N, Williams Patricia K, Anderson Michael P, Bedwell Susan, Miller Jamie L
J Pediatr Pharmacol Ther. 2019 Mar-Apr;24(2):148-155. doi: 10.5863/1551-6776-24.2.148.
To compare the modified Finnegan Scoring System (modified Finnegan) with an Adjusted Scoring System Criteria (adjusted Finnegan) for infants after cardiothoracic surgery with iatrogenic opioid abstinence syndrome (IOAS).
This was a retrospective, observational pilot study. This study was conducted in a tertiary care academic hospital. Infants after cardiothoracic surgery with IOAS transferred between the pediatric intensive care unit and neonatal intensive care unit between January 1, 2014, and January 31, 2016, were included retrospectively. The main outcome variable was to compare the area under the curve for the mean modified Finnegan versus adjusted Finnegan.
Twenty-five patients were included in the study. Twenty patients with at least 30 scores were included in the final analysis. Overall, the modified Finnegan scores were at least 2 points higher than the adjusted Finnegan. The difference in area under the curve was 34.6 (p < 0.001).
Use of the modified Finnegan tool for older infants with IOAS could overestimate withdrawal, leading to unnecessary interventions.
比较改良的芬尼根评分系统（改良芬尼根）与调整后的评分系统标准（调整后芬尼根）用于心胸外科手术后患有医源性阿片类药物戒断综合征（IOAS）的婴儿的情况。
这是一项回顾性观察性试点研究。该研究在一家三级医疗学术医院进行。回顾性纳入2014年1月1日至2016年1月31日期间在儿科重症监护病房和新生儿重症监护病房之间转诊的患有IOAS的心胸外科手术后婴儿。主要结局变量是比较平均改良芬尼根与调整后芬尼根的曲线下面积。
25例患者纳入研究。最终分析纳入了20例至少得30分的患者。总体而言，改良芬尼根评分比调整后芬尼根至少高2分。曲线下面积差异为34.6（p<0.001）。
将改良芬尼根工具用于患有IOAS的大龄婴儿可能会高估戒断情况，导致不必要的干预。
