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Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells.评估已建立的技术以确定人类多能干细胞的发育和恶性潜能。
Nat Commun. 2018 May 15;9(1):1925. doi: 10.1038/s41467-018-04011-3.
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Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells.国际干细胞库倡议研讨会活动报告:人类多能干细胞种子库存储的当前障碍和进展。
Stem Cells Transl Med. 2017 Nov;6(11):1956-1962. doi: 10.1002/sctm.17-0144. Epub 2017 Oct 24.
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Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications.评估人类多能干细胞及其衍生物用于临床应用的安全性。
Stem Cell Reports. 2017 Jul 11;9(1):1-4. doi: 10.1016/j.stemcr.2017.05.029.
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Good Cell Culture Practice for stem cells and stem-cell-derived models.良好的干细胞和干细胞衍生模型的细胞培养规范。
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Whole-Genome Sequencing of a Healthy Aging Cohort.一个健康老龄化队列的全基因组测序
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Curr Stem Cell Rep. 2015;1(2):110-117. doi: 10.1007/s40778-015-0011-7.
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Points to consider in the development of seed stocks of pluripotent stem cells for clinical applications: International Stem Cell Banking Initiative (ISCBI).用于临床应用的多能干细胞种子库开发中需考虑的要点:国际干细胞库倡议组织(ISCBI)。
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Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.国际干细胞研究协会对人类胚胎干细胞系的特征描述
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国际干细胞库倡议研讨会报告,由全球诱导多能干细胞治疗联盟与哈佛干细胞研究所联合主办,2017 年于波士顿召开。

A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017.

机构信息

Division of Intractable Diseases, Korea National Stem Cell Bank, Center for Biomedical Sciences, Korea National Institute of Health, Cheongju, Korea.

Wellcome Sanger Institute, Cambridge, United Kingdom.

出版信息

Stem Cells. 2019 Sep;37(9):1130-1135. doi: 10.1002/stem.3003. Epub 2019 Aug 6.

DOI:10.1002/stem.3003
PMID:31021472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7187460/
Abstract

This report summarizes the recent activity of the International Stem Cell Banking Initiative held at Harvard Stem Cell Institute, Boston, MA, USA, on June 18, 2017. In this meeting, we aimed to find consensus on ongoing issues of quality control (QC), safety, and efficacy of human pluripotent stem cell banks and their derivative cell therapy products for the global harmonization. In particular, assays for the QC testing such as pluripotency assays test and general QC testing criteria were intensively discussed. Moreover, the recent activities of global stem cell banking centers and the regulatory bodies were briefly summarized to provide an overview on global developments and issues. Stem Cells 2019;37:1130-1135.

摘要

本报告总结了 2017 年 6 月 18 日在美国马萨诸塞州波士顿哈佛干细胞研究所举行的国际干细胞库倡议的最新活动。在本次会议上,我们旨在就人类多能干细胞库及其衍生细胞治疗产品的质量控制 (QC)、安全性和有效性的当前问题达成全球协调一致的共识。特别是,对 QC 检测(如多能性检测和一般 QC 检测标准)的检测方法进行了深入讨论。此外,简要总结了全球干细胞库中心和监管机构的最新活动,以提供全球发展和问题的概述。干细胞 2019;37:1130-1135.