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催产素无法影响正常男性体内睾酮、催乳素、黄体生成素和促卵泡激素的分泌。

The inability of oxytocin to influence the secretion of testosterone, prolactin, luteinizing and follicle-stimulating hormone in normal men.

作者信息

Kirilov G, Saharieva S, Javorska N

出版信息

Exp Clin Endocrinol. 1986 Nov;88(1):115-8. doi: 10.1055/s-0029-1210585.

DOI:10.1055/s-0029-1210585
PMID:3102264
Abstract

Recently controversial data has been obtained about the endocrine effects of the neurohypophyseal hormone oxytocin both in vitro and in vivo. We measured testosterone, prolactin, LH and FSH by specific radioimmunoassay in seven healthy adult males before, during and after intravenous infusion of either synthetic oxytocin (4IU/100 ml/120 min) or saline. The findings clearly demonstrate that in men oxytocin does not affect plasma prolactin, LH and FSH. Our results do not establish an effect of oxytocin on basal testosterone release in healthy male subjects.

摘要

最近,关于神经垂体激素催产素在体外和体内的内分泌作用,已经获得了有争议的数据。我们通过特异性放射免疫分析法,在7名健康成年男性静脉输注合成催产素(4IU/100 ml/120分钟)或生理盐水之前、期间和之后,测量了睾酮、催乳素、促黄体生成素(LH)和促卵泡生成素(FSH)。研究结果清楚地表明,在男性中,催产素不会影响血浆催乳素、LH和FSH。我们的结果并未证实催产素对健康男性受试者基础睾酮释放有影响。

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Exp Clin Endocrinol. 1986 Nov;88(1):115-8. doi: 10.1055/s-0029-1210585.
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引用本文的文献

1
Association between neuropeptide oxytocin and male infertility.神经肽催产素与男性不育的关系。
J Assist Reprod Genet. 2010 Sep;27(9-10):525-31. doi: 10.1007/s10815-010-9451-2. Epub 2010 Aug 14.
2
Drug-induced changes in prolactin secretion. Clinical implications.药物引起的催乳素分泌变化。临床意义。
Med Toxicol Adverse Drug Exp. 1988 Nov-Dec;3(6):463-98. doi: 10.1007/BF03259897.