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健康人群在改善认知功能背景下滥用药物增强剂的伦理问题。

Ethical aspects of the abuse of pharmaceutical enhancements by healthy people in the context of improving cognitive functions.

作者信息

Tomažič Tina, Čelofiga Anita Kovačič

机构信息

Faculty of Electrical Engineering and Computer Science, University of Maribor, Institute for Media Communications, Koroška cesta 46, 2000, Maribor, Slovenia.

Alma Mater Europaea, Slovenska ulica 17, 2000, Maribor, Slovenia.

出版信息

Philos Ethics Humanit Med. 2019 Apr 25;14(1):7. doi: 10.1186/s13010-019-0076-5.

DOI:10.1186/s13010-019-0076-5
PMID:31023334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6482530/
Abstract

Better memory, greater motivation and concentration lead to greater productivity, efficiency and performance, all of which are features that are highly valued in a modern society focused on productivity. In the effort for better cognitive abilities, otherwise healthy individuals use cognitive enhancers (also known as nootropics), medicines for the treatment of cognitive deficits of patients with various disorders and health problems, such as Alzheimer's disease, schizophrenia, stroke, Attention Deficit Hyperactivity Disorder or ageing. The use of these is more common in professions with emphasised cognitive abilities, or in occupations that require more attention, focus and alertness. Their use is also associated with the general working population, in that they are supposed to use them to alleviate the effects of sleep deprivation and to cope with increasing workloads.In the paper, we are addressing the ethical issue and the dilemmas of the use of pharmaceutical enhancements by healthy people who have no medical reason for taking such substances, in the context of improving their cognitive functions.

摘要

更好的记忆力、更强的动力和注意力能带来更高的生产力、效率和表现,所有这些都是在注重生产力的现代社会中备受重视的特征。为了提升认知能力,原本健康的个体使用认知增强剂(也称为益智药),这些药物用于治疗患有各种疾病和健康问题(如阿尔茨海默病、精神分裂症、中风、注意力缺陷多动障碍或衰老)患者的认知缺陷。在认知能力要求较高的职业中,或者在需要更多注意力、专注力和警觉性的工作中,这些药物的使用更为普遍。它们的使用也与普通劳动人口相关,因为人们认为他们使用这些药物是为了减轻睡眠剥夺的影响并应对不断增加的工作量。在本文中,我们将探讨在改善认知功能的背景下,无医学理由服用此类物质的健康人使用药物增强剂所涉及的伦理问题和困境。

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引用本文的文献

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Healthcare (Basel). 2022 May 24;10(6):972. doi: 10.3390/healthcare10060972.
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Pharmacological Neuroenhancement: Current Aspects of Categorization, Epidemiology, Pharmacology, Drug Development, Ethics, and Future Perspectives.药理学神经增强:分类、流行病学、药理学、药物开发、伦理学的当前方面和未来展望。
Neural Plast. 2021 Jan 13;2021:8823383. doi: 10.1155/2021/8823383. eCollection 2021.

本文引用的文献

1
Neuroethical issues in cognitive enhancement: Modafinil as the example of a workplace drug?认知增强中的神经伦理问题:以莫达非尼为例探讨工作场所药物?
Brain Neurosci Adv. 2019 Feb 15;3:2398212818816018. doi: 10.1177/2398212818816018. eCollection 2019 Jan-Dec.
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Pharmacological cognitive enhancement among non-ADHD individuals-A cross-sectional study in 15 countries.非 ADHD 个体的药物认知增强——15 个国家的横断面研究。
Int J Drug Policy. 2018 Aug;58:104-112. doi: 10.1016/j.drugpo.2018.05.009. Epub 2018 Jun 11.
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Amoral enhancement.非道德增强。
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Philos Ethics Humanit Med. 2016 Sep 19;11(1):7. doi: 10.1186/s13010-016-0037-1.
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Varsity Medical Ethics Debate 2015: should nootropic drugs be available under prescription on the NHS?2015年大学医学伦理辩论会:益智药是否应通过英国国家医疗服务体系(NHS)处方获取?
Philos Ethics Humanit Med. 2016 Sep 13;11(1):6. doi: 10.1186/s13010-016-0041-5.
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Focusing the Neuroscience and Societal Implications of Cognitive Enhancers.聚焦认知增强剂的神经科学及社会影响。
Clin Pharmacol Ther. 2017 Feb;101(2):170-172. doi: 10.1002/cpt.457. Epub 2016 Sep 23.
8
Moral and social reasons to acknowledge the use of cognitive enhancers in competitive-selective contexts.在竞争选拔环境中认可使用认知增强剂的道德和社会原因。
BMC Med Ethics. 2016 Mar 29;17:18. doi: 10.1186/s12910-016-0102-8.
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A survey of substance use for cognitive enhancement by university students in the Netherlands.荷兰大学生认知增强物质使用情况调查。
Front Syst Neurosci. 2015 Feb 17;9:10. doi: 10.3389/fnsys.2015.00010. eCollection 2015.
10
Robust resilience and substantial interest: a survey of pharmacological cognitive enhancement among university students in the UK and Ireland.强大的恢复力与浓厚的兴趣:对英国和爱尔兰大学生药物认知增强情况的调查
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