Brühl Annette B, d'Angelo Camilla, Sahakian Barbara J
Department of Psychiatry, Behavioural and Clinical Neuroscience Institute, University of Cambridge, Cambridge, UK.
Department of Psychiatry, Psychotherapy, and Psychosomatics, Psychiatric Hospital, University of Zurich, Zurich, Switzerland.
Brain Neurosci Adv. 2019 Feb 15;3:2398212818816018. doi: 10.1177/2398212818816018. eCollection 2019 Jan-Dec.
The use of cognitive-enhancing drugs by healthy individuals has been a feature for much of recorded history. Cocaine and amphetamine are modern cases of drugs initially enthusiastically acclaimed for enhancing cognition and mood. Today, an increasing number of healthy people are reported to use cognitive-enhancing drugs, as well as other interventions, such as non-invasive brain stimulation, to maintain or improve work performance. Cognitive-enhancing drugs, such as methylphenidate and modafinil, which were developed as treatments, are increasingly being used by healthy people. Modafinil not only affects 'cold' cognition, but also improves 'hot' cognition, such as emotion recognition and task-related motivation. The lifestyle use of 'smart drugs' raises both safety concerns as well as ethical issues, including coercion and increasing disparity in society. As a society, we need to consider which forms of cognitive enhancement (e.g. pharmacological, exercise, lifelong learning) are acceptable and for which groups under what conditions and by what methods we would wish to improve and flourish.
健康个体使用认知增强药物在大部分有记载的历史中一直存在。可卡因和安非他命是现代版的药物,最初因能增强认知和改善情绪而备受推崇。如今,据报道越来越多的健康人使用认知增强药物以及其他干预手段,如非侵入性脑刺激,来维持或提高工作表现。像哌醋甲酯和莫达非尼这类作为治疗药物研发出来的认知增强药物,正越来越多地被健康人使用。莫达非尼不仅影响“冷”认知,还能改善“热”认知,如情绪识别和与任务相关的动机。“聪明药”在生活方式中的使用引发了安全担忧以及伦理问题,包括强迫行为和社会差距日益加大等。作为一个社会,我们需要思考哪种形式的认知增强(如药物、锻炼、终身学习)是可接受的,以及在何种条件下、通过何种方法,我们希望哪些群体能够得到改善并蓬勃发展。