Department of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, United States.
Department of Neurological Surgery, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, United States.
J Clin Neurosci. 2019 Jun;64:214-219. doi: 10.1016/j.jocn.2019.03.061. Epub 2019 Apr 22.
Previous work in directional tuning for brain machine interfaces has primarily relied on algorithm sorted neuronal action potentials in primary motor cortex. However, local field potential has been utilized to show directional tuning in macaque studies, and inferior parietal cortex has shown increased neuronal activity in reaching tasks that relied on MRI imaging. In this study we utilized local field potential recordings from a human subject performing a delayed reach task and show that high frequency band (76-100 Hz) spectral power is directionally tuned to different reaching target locations during an active reach. We also show that during the delay phase of the task, directional tuning is present in areas of the inferior parietal cortex, in particular, the supramarginal gyrus.
先前在脑机接口的方向调谐方面的工作主要依赖于初级运动皮层中经算法排序的神经元动作电位。然而，在猕猴研究中已经利用局部场电位来显示方向调谐，并且在依赖于 MRI 成像的到达任务中，下顶叶皮层显示出增加的神经元活动。在这项研究中，我们利用了人类受试者在进行延迟到达任务时的局部场电位记录，并表明在主动到达期间，高频带（76-100 Hz）谱功率对不同的到达目标位置具有方向性调谐。我们还表明，在任务的延迟阶段，下顶叶皮层的区域存在方向调谐，特别是缘上回。
