Mooshagian Eric, Holmes Charles D, Snyder Lawrence H
Department of Neuroscience, Washington University School of Medicine, St. Louis, MO, USA.
Department of Cognitive Science, University of California San Diego, La Jolla, CA, USA.
Nat Commun. 2021 May 4;12(1):2514. doi: 10.1038/s41467-021-22701-3.
Primates use their arms in complex ways that frequently require coordination between the two arms. Yet the planning of bimanual movements has not been well-studied. We recorded spikes and local field potentials (LFP) from the parietal reach region (PRR) in both hemispheres simultaneously while monkeys planned and executed unimanual and bimanual reaches. From analyses of interhemispheric LFP-LFP and spike-LFP coherence, we found that task-specific information is shared across hemispheres in a frequency-specific manner. This shared information could arise from common input or from direct communication. The population average unit activity in PRR, representing PRR output, encodes only planned contralateral arm movements while beta-band LFP power, a putative PRR input, reflects the pattern of planned bimanual movement. A parsimonious interpretation of these data is that PRR integrates information about the movement of the left and right limbs, perhaps in service of bimanual coordination.
灵长类动物以复杂的方式使用它们的手臂，这常常需要双臂之间的协调。然而，双手运动的规划尚未得到充分研究。我们在猴子规划和执行单手及双手够物动作时，同时记录了两个半球顶叶够物区域（PRR）的尖峰信号和局部场电位（LFP）。通过对半球间LFP-LFP和尖峰-LFP相干性的分析，我们发现特定任务信息以频率特异性的方式在半球间共享。这种共享信息可能源于共同输入或直接通信。PRR中的群体平均单位活动代表PRR输出，仅编码计划中的对侧手臂运动，而β波段LFP功率（一种假定的PRR输入）反映了计划中的双手运动模式。对这些数据的一种简洁解释是，PRR整合了左右肢体运动的信息，这可能有助于双手协调。
