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撒哈拉以南非洲地区的心血管疾病与艾滋病毒感染:公共卫生和研究议程中的优先事项错位?

Cardiovascular Disease and HIV Infection in Sub-Saharan Africa: Misplaced Priorities in the Public Health and Research Agendas?

作者信息

Bain Luchuo Engelbert, Gwain Gerald Chia

机构信息

Faculty of Science, Athena Institute for Research on Innovation and Communication in Health and Life Sciences, Vrije Universiteit, Amsterdam, Netherlands.

Department of Behavioral Health, Northwest Hospital, Randallstown, MD, United States.

出版信息

Front Cardiovasc Med. 2019 Apr 5;6:35. doi: 10.3389/fcvm.2019.00035. eCollection 2019.

Abstract

The effectiveness of combined antiretroviral therapy, not only allows people living with HIV (PLHIV) to live longer, but also exposes them to extra cardiometabolic risks. The recent report of the International AIDS (Acquired Immune Deficiency Syndrome) Society and the Lancet commission are clear on the fact that, the world is not on track regarding ending the HIV/AIDS pandemic by the year 2030 (UNAIDS 90-90-90 targets). We highlight the priority public health interventions, as well as research actions to cope with this almost inevitable triple burden of disease for the continent. Improvement of routine data collection within the health systems strengthening agenda, prioritization of primary health care as the cornerstone of an effective health care system to contain HIV as a chronic disease, and multiplication of large cohort studies in Sub-Saharan Africa are the main public health and research imperatives.

摘要

联合抗逆转录病毒疗法不仅能让艾滋病毒感染者活得更长,还使他们面临额外的心脏代谢风险。国际艾滋病协会和《柳叶刀》委员会最近的报告明确指出,世界在2030年结束艾滋病毒/艾滋病大流行(联合国艾滋病规划署90-90-90目标)方面进展不顺。我们强调了优先的公共卫生干预措施以及应对非洲大陆这种几乎不可避免的三重疾病负担的研究行动。加强卫生系统议程中常规数据收集的改进、将初级卫生保健作为有效卫生保健系统基石以将艾滋病毒作为慢性病加以控制的优先安排,以及在撒哈拉以南非洲增加大型队列研究,是主要的公共卫生和研究要务。

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Cardiovascular Risk Prediction Functions Underestimate Risk in HIV Infection.心血管风险预测模型在 HIV 感染中的风险预测存在偏差。
Circulation. 2018 May 22;137(21):2203-2214. doi: 10.1161/CIRCULATIONAHA.117.028975. Epub 2018 Feb 14.

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