Meyerson B A, Boëthius J, Carlsson A M
Appl Neurophysiol. 1978;41(1-4):57-65. doi: 10.1159/000102401.
Electrical stimulation of the periventricular and periaqueductal gray matter via a percutaneous electrode appears to be a useful method for relieving cancer pain with midline and bilateral distribution. Due to the nondestructive character and the minor surgical risks involved in this procedure it may be tried before considering bilateral cordotomy or myelotomy. A possible mechanism of action or at least a contributive factor to the pain relief is the activation of endorphins.
经皮电极对脑室周围和导水管周围灰质进行电刺激似乎是缓解中线和双侧分布癌症疼痛的一种有效方法。由于该手术具有非破坏性且手术风险较小，因此在考虑双侧脊髓前侧柱切断术或脊髓切开术之前可以尝试使用。其可能的作用机制或至少是疼痛缓解的一个促成因素是内啡肽的激活。
