人类中脑导水管周围灰质背侧刺激
Dorsal periaqueductal gray-matter stimulation in humans.
作者信息
Hosobuchi Y
出版信息
Pacing Clin Electrophysiol. 1987 Jan;10(1 Pt 2):213-6. doi: 10.1111/j.1540-8159.1987.tb05951.x.
Abstract
Seven patients suffering intractable pain from head and neck cancer (age 48-73, mean 57.5 years) underwent acute stimulation of dorsal periaqueductal gray matter (PAG) with immediate cessation of pain. Two patients received chronic PAG stimulation with relief of pain during stimulation. The effect was not reversed by naloxone and there were no changes in CSF peptides.
摘要
7例头颈部癌症引起顽固性疼痛的患者（年龄48 - 73岁，平均57.5岁）接受了中脑导水管周围灰质（PAG）背侧的急性刺激，疼痛随即缓解。2例患者接受了PAG慢性刺激，刺激期间疼痛缓解。纳洛酮不能逆转这种效应，脑脊液肽也无变化。
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