Feder H M, Shanley J D, Barbera J A
Pediatr Infect Dis J. 1987 Jan;6(1):24-8. doi: 10.1097/00006454-198701000-00007.
We reviewed the charts of 59 pediatric and adult patients hospitalized because of animal bites (46 dog bites, 10 cat bites, 3 monkey bites). The bites of 40 of the 59 patients were infected at the time of admission. Gram-stained specimens correctly predicted the infecting bacteria in only 5 of 20 cases. Eighty-three percent of the bacterial isolates were penicillin-susceptible. Before admission 14 patients had received outpatient antibiotic prophylaxis and the infections in 11 of these 14 patients were caused by bacteria susceptible to the prophylactic antibiotic. Complications were more common if antimicrobial therapy had not been altered according to susceptibility testing results. Of the 59 patients 19 were admitted immediately after being bitten because of severe uninfected bites. Of these 19 patients 18 received prophylactic antibiotics and none developed a serious complication.
我们查阅了59例因动物咬伤而住院的儿科和成年患者的病历(46例狗咬伤,10例猫咬伤,3例猴子咬伤)。59例患者中有40例在入院时伤口已感染。革兰氏染色标本仅在20例中的5例中正确预测了感染细菌。83%的细菌分离株对青霉素敏感。入院前,14例患者接受了门诊抗生素预防治疗,这14例患者中有11例的感染是由对预防性抗生素敏感的细菌引起的。如果未根据药敏试验结果调整抗菌治疗,并发症则更为常见。59例患者中有19例因严重的未感染咬伤在被咬后立即入院。在这19例患者中,18例接受了预防性抗生素治疗,无一例出现严重并发症。