Civil, Environmental, and Geodetic Engineering, The Ohio State University, Columbus, OH 43210, USA.
Department of Energy, Environmental, and Chemical Engineering, Washington University in St Louis, St Louis, MO 63130, USA.
Trends Microbiol. 2019 Aug;27(8):670-677. doi: 10.1016/j.tim.2019.03.011. Epub 2019 Apr 25.
Now is an opportune time to foster collaborations across sectors and geographical boundaries to enable development of best practices for drinking water (DW) microbiome research, focusing on accuracy and reproducibility of meta-omic techniques (while learning from past microbiome projects). A large-scale coordinated effort that builds on this foundation will enable the urgently needed comprehensive spatiotemporal understanding and control of DW microbiomes by engineering interventions to protect public health. This opinion paper highlights the need to initiate and conduct a large-scale coordinated DW microbiome project by addressing key knowledge gaps and recommends a roadmap for this effort.
现在是促进跨部门和地理边界合作的好时机，以便为饮用水（DW）微生物组研究制定最佳实践，重点是元组学技术的准确性和可重复性（同时从过去的微生物组项目中吸取经验教训）。在此基础上开展的大规模协调努力将通过工程干预来保护公众健康，从而实现对 DW 微生物组的全面、急需的时空理解和控制。本观点文件强调了通过解决关键知识差距来启动和开展大规模协调的 DW 微生物组项目的必要性，并为这一努力推荐了路线图。
