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一名患有隐球菌性脑膜炎的艾滋病患者出现视力丧失。

Vision loss in an AIDS patient with cryptococcal meningitis.

作者信息

Aldhaleei Wafa Ali, Bhagavathula Akshaya Srikanth, Alhajeri Ameera

机构信息

Internal Medicine Specialist, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.

Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates.

出版信息

Med Mycol Case Rep. 2019 Apr 16;24:51-53. doi: 10.1016/j.mmcr.2019.04.001. eCollection 2019 Jun.

DOI:10.1016/j.mmcr.2019.04.001
PMID:31032178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6479074/
Abstract

Cryptococcal meningitis is considered one of the AIDS-defining illness and has been reported to be associated with neurological sequels. However, acute vision loss as presenting complaint is rare in Cryptococcal meningitis. Management of Cryptococcal meningitis with antifungal therapy may not lead to favourable outcomes and may necessitate the need for invasive intervention. We report a case of acute bilateral visual loss secondary to Cryptococcal meningitis.

摘要

隐球菌性脑膜炎被认为是艾滋病界定疾病之一，据报道与神经后遗症有关。然而，以急性视力丧失为主诉的情况在隐球菌性脑膜炎中较为罕见。用抗真菌疗法治疗隐球菌性脑膜炎可能不会带来良好的结果，可能需要进行侵入性干预。我们报告一例继发于隐球菌性脑膜炎的急性双侧视力丧失病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ba/6479074/05a817f779ae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ba/6479074/ff0514be7353/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ba/6479074/05a817f779ae/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ba/6479074/ff0514be7353/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2ba/6479074/05a817f779ae/gr2.jpg

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本文引用的文献

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Am J Ophthalmol Case Rep. 2018 Jan 31;10:51-54. doi: 10.1016/j.ajoc.2018.01.045. eCollection 2018 Jun.
2
Visual Disturbance in Patients with Cryptococcal Meningitis: The Road Ahead.隐球菌性脑膜炎患者的视觉障碍：未来之路
J Neurosci Rural Pract. 2017 Jan-Mar;8(1):151-152. doi: 10.4103/0976-3147.193560.
3
Acute vision loss in post-partum period as presenting symptom of HIV-associated cryptococcal meningitis-an unusual case report.
产后急性视力丧失作为HIV相关隐球菌性脑膜炎的首发症状——一例罕见病例报告
BMC Infect Dis. 2016 Oct 19;16(1):582. doi: 10.1186/s12879-016-1925-0.
4
Visual evoked potentials show strong positive association with intracranial pressure in patients with cryptococcal meningitis.视觉诱发电位显示，隐球菌性脑膜炎患者的视觉诱发电位与颅内压呈强正相关。
Arq Neuropsiquiatr. 2015 Apr;73(4):309-13. doi: 10.1590/0004-282X20150002. Epub 2015 Apr 1.
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Reversible blindness in cryptococcal meningitis with normal intracranial pressure: case report and review of the literature.颅内压正常的隐球菌性脑膜炎致可逆性失明：病例报告及文献复习。
Clin Infect Dis. 2014 Jul 15;59(2):310-3. doi: 10.1093/cid/ciu216. Epub 2014 Apr 4.
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A neglected epidemic: fungal infections in HIV/AIDS.被忽视的流行病：HIV/AIDS 中的真菌感染。
Trends Microbiol. 2014 Mar;22(3):120-7. doi: 10.1016/j.tim.2014.01.001. Epub 2014 Feb 13.
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Ocular complications of cryptococcal meningitis in patients with HIV: report of two cases and review of the literature.HIV 患者隐球菌性脑膜炎的眼部并发症：两例报告及文献复习
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8
HIV/AIDS and blindness.艾滋病毒/艾滋病与失明
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Clin Neurol Neurosurg. 1998 Mar;100(1):51-2. doi: 10.1016/s0303-8467(97)00119-4.
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Ophthalmic manifestations of infections with Cryptococcus neoformans in patients with the acquired immunodeficiency syndrome.获得性免疫缺陷综合征患者新型隐球菌感染的眼部表现。
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