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基于人群的队列研究:医院分娩量、地理可及性与产科结局。

Population-based cohort study of hospital delivery volume, geographic accessibility, and obstetric outcomes.

机构信息

Primary Healthcare Research Unit, Discipline of Family Medicine, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.

Department of Geography, Faculty of Humanities and Social Sciences, Memorial University of Newfoundland, St. John's, NL, Canada.

出版信息

Int J Gynaecol Obstet. 2019 Jul;146(1):95-102. doi: 10.1002/ijgo.12832. Epub 2019 May 17.

Abstract

OBJECTIVE

To determine associations between geographic accessibility, delivery volume, and obstetric outcomes.

METHODS

Population-based cohort study of linked hospital administrative, census, and geospatial data (2006-2009) from all Canadian jurisdictions except Quebec. Perinatal mortality and major maternal morbidity/mortality were compared across categories of road distance and hospital delivery volume.

RESULTS

Among 820 761 mothers delivering 827 504 neonates, travel distance had minimal effect on perinatal mortality. Compared with mothers travelling 0-9 km, the odds of adverse maternal outcomes was decreased for women travelling modest distances (20-49 km, odds ratio, 0.80 [95% confidence interval, 0.75-0.86]), and increased thereafter (50-99 km, 0.99 [0.89-1.10]; 200-299 km, 1.44 [1.10-1.87]; >400 km, 2.22 [1.06-4.63]). Relative to high-volume hospitals (>2500 deliveries/year), adverse maternal outcomes were less likely for hospitals with 1000-2499 (0.90 [0.86-0.95]), and roughly equivalent for hospitals with 200-499 (1.34 [1.22-1.48]) and 500-999 (1.27 [1.17-1.39]) deliveries/year. Odds of perinatal mortality ranged from 1.04 (0.73-1.49; 100-199 deliveries/year) to 1.50 (1.04-2.16; 50-99 deliveries/year); the pattern did not suggest causality.

CONCLUSION

Maternal outcomes worsen when travel distance is greater than 200 km, and improve when delivery volume exceeds 1000 deliveries per year.

摘要

目的

确定地理可达性、分娩量与产科结局之间的关系。

方法

对来自加拿大除魁北克以外所有司法管辖区的医院行政、人口普查和地理空间数据(2006-2009 年)进行基于人群的队列研究。比较了不同道路距离和医院分娩量类别下的围产儿死亡率和主要产妇发病率/死亡率。

结果

在 820761 名分娩 827504 名新生儿的母亲中,旅行距离对围产儿死亡率的影响很小。与旅行距离 0-9 公里的母亲相比,旅行距离适中(20-49 公里,比值比 0.80 [95%置信区间,0.75-0.86])的母亲发生不良母婴结局的几率降低,此后旅行距离每增加 100 公里,不良母婴结局的几率增加(50-99 公里,0.99 [0.89-1.10];200-299 公里,1.44 [1.10-1.87];>400 公里,2.22 [1.06-4.63])。与高容量医院(>2500 次分娩/年)相比,分娩量在 1000-2499 次之间的医院发生不良母婴结局的几率较低(0.90 [0.86-0.95]),而分娩量在 200-499 次和 500-999 次之间的医院则大致相当(1.34 [1.22-1.48]和 1.27 [1.17-1.39])。围产儿死亡率的比值比范围为 1.04(0.73-1.49;100-199 次分娩/年)至 1.50(1.04-2.16;50-99 次分娩/年);这种模式并不能表明因果关系。

结论

当旅行距离大于 200 公里时,产妇结局恶化,而当分娩量超过每年 1000 次时,产妇结局改善。

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