Lin Feiyan, Song Jinru, Hua Ying, Pan Liangli, Guo Yao, Hu Gang, Yang Bin
Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China.
J Cosmet Dermatol. 2025 Jan;24(1):e16645. doi: 10.1111/jocd.16645. Epub 2024 Nov 26.
Periocular static wrinkles, which are common cosmetic concerns, lack an established effective treatment. Microneedling radio frequency (MNRF) has shown promise in skin rejuvenation; however, there is limited objective information on its long-term effectiveness with regard to periocular static wrinkles.
This study aimed to evaluate the clinical efficacy and safety of MNRF treatment for periocular static wrinkles.
Eighteen participants with moderate to severe wrinkles were enrolled in this study. MNRF treatment was applied to the periocular skin using MicroRF9 microneedles, which have a depth of 0.5-1.5 mm and a pulse width of 200-300 ms. MNRF treatment was administered twice with a 1-month interval, and the participants were followed up for 6 months. The evaluation included four areas, namely the outer canthi, lower eyelid, inner canthi, and upper eyelid, by using clinical assessments and Antera 3D measurements by digitalized images and grading by clinicians.
The results showed significant improvement in all four areas assessed. Participants expressed high satisfaction with the treatment, and any adverse events, such as mild pain and redness, were temporary and resolved within a week.
These findings confirm that MNRF is a safe and effective method for reducing periocular static wrinkles.
眼周静态皱纹是常见的美容问题，目前缺乏成熟有效的治疗方法。微针射频（MNRF）在皮肤年轻化方面已显示出前景；然而，关于其对眼周静态皱纹的长期有效性的客观信息有限。
本研究旨在评估MNRF治疗眼周静态皱纹的临床疗效和安全性。
18名有中度至重度皱纹的参与者纳入本研究。使用深度为0.5 - 1.5毫米、脉冲宽度为200 - 300毫秒的MicroRF9微针将MNRF治疗应用于眼周皮肤。MNRF治疗间隔1个月进行两次，对参与者随访6个月。通过临床评估、数字化图像的Antera 3D测量以及临床医生分级，对包括外眦、下眼睑、内眦和上眼睑在内的四个区域进行评估。
结果显示在所有四个评估区域均有显著改善。参与者对治疗表示高度满意，任何不良事件，如轻度疼痛和发红，都是暂时的，且在一周内消退。
这些发现证实MNRF是减少眼周静态皱纹的一种安全有效的方法。
