Department of Psychology, University of Houston, Houston, TX (AHR, JB, MJZ); Department of Behavioral Sciences, University of Texas MD Anderson Cancer Center, Houston, TX (MJZ); Health Institute, University of Houston, Houston, TX (MJZ); Department of Psychology, University of New Mexico, Albuquerque, NM (KEV).
J Addict Med. 2020 Jan/Feb;14(1):26-31. doi: 10.1097/ADM.0000000000000538.
Chronic pain affects a significant number of individuals in the United States and is associated with several negative health-related outcomes, including possibility of opioid misuse and disability. The identification of factors associated with both opioid misuse and disability is of critical public health importance, and significant research suggests that pain severity has been shown to be associated with both. Pain-related anxiety has been uniquely associated with both opioid misuse and disability, yet little research has examined pain-related anxiety as a potential mechanism linking pain severity with opioid misuse and disability.
Therefore, the current study examined whether pain-related anxiety explains, in part, the relationship between pain severity, opioid misuse, and disability among 396 adults with chronic pain (55.8% female, Mage 36.61, SD 11.40).
Cross-sectional analyses indicated that pain-related anxiety significantly mediated the relationship between pain severity, opioid misuse outcomes, and psychosocial disability, but not physical disability.
These results build upon the literature indicating the importance of pain-related anxiety in those with chronic pain by suggesting this construct may account, in part, for the relation of pain intensity to opioid misuse and psychosocial disability. Future research should longitudinally examine these associations.
慢性疼痛影响了美国相当数量的人群，与多种负面健康相关后果相关，包括阿片类药物滥用和残疾的可能性。确定与阿片类药物滥用和残疾都相关的因素对于公共卫生至关重要，大量研究表明，疼痛严重程度与两者都有关。与疼痛相关的焦虑与阿片类药物滥用和残疾都有独特的关联，但很少有研究探讨疼痛相关的焦虑是否是将疼痛严重程度与阿片类药物滥用和残疾联系起来的潜在机制。
因此，本研究考察了疼痛相关的焦虑是否部分解释了 396 名慢性疼痛成年人（55.8%为女性，平均年龄为 36.61，标准差为 11.40）中疼痛严重程度、阿片类药物滥用和残疾之间的关系。
横断面分析表明，疼痛相关的焦虑显著中介了疼痛严重程度、阿片类药物滥用结果和心理社会残疾之间的关系，但与身体残疾无关。
这些结果进一步证明了疼痛相关焦虑在慢性疼痛患者中的重要性，表明该结构可能部分解释了疼痛强度与阿片类药物滥用和心理社会残疾之间的关系。未来的研究应从纵向角度检查这些关联。
