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免疫功能正常和免疫功能低下人群中吉米环病毒DNA的低流行率。

Low prevalence of Gemycircularvirus DNA in immunocompetent and immunocompromised subjects.

作者信息

Macera Lisa, Spezia Pietro Giorgio, Medici Chiara, Falasca Francesca, Sciandra Ilaria, Antonelli Guido, Focosi Daniele, Pistello Mauro, Maggi Fabrizio

机构信息

Department of Translational Research, University of Pisa, Pisa Italy.

Virology Division, Pisa University Hospital, Pisa, Italy.

出版信息

New Microbiol. 2019 Apr;42(2):118-120. Epub 2019 Apr 29.

Abstract

Gemycircularviruses (GemyCV) are a vast array of viruses belonging to the Genomoviridae family. Prevalence and pathogenesis in humans are still poorly understood. Different GemyCV species were investigated in 661 Italian subjects by species-specific PCRs. Only the GemyCV-C1c species was detected, with low prevalence and the highest rate in HIV immunosuppressed patients.

摘要

微小环状病毒(GemyCV)是一大类属于基因组病毒科的病毒。人们对其在人类中的流行情况和发病机制仍知之甚少。通过种特异性聚合酶链反应(PCR)对661名意大利受试者中的不同GemyCV物种进行了调查。仅检测到GemyCV-C1c物种,其患病率较低,在人类免疫缺陷病毒(HIV)免疫抑制患者中的检出率最高。

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