State Epidemiologist, State Institute of Health & Family Welfare, Shimla, Himachal Pradesh, India.
Department of Health & Family Welfare, Civil Hospital Theog, Shimla, Himachal Pradesh, India.
Hum Vaccin Immunother. 2019;15(11):2612-2614. doi: 10.1080/21645515.2019.1608131. Epub 2019 May 22.
On January 4, 2019 an eight-year-old girl child was bitten by a suspected rabid dog over the left parotid region. After a 17-h delay, the child was brought for rabies postexposure prophylaxis (PEP) at Civil Hospital Theog and was administered complete PEP. On January 29, 2019, the child was again brought to Theog Hospital with complaints of having fever, difficulty in walking, neck drop, and ptosis. On examination, pediatrician found photophobia, phonophobia, and hydrophobia and subsequently the patient died of cardiac arrest. On postmortem examination, the facial nerve was found dissected and injured at the inner end of the parotid gland. A severed end toward the brain was swollen and edematous. The entire brain was extracted and sent to Central Research Institute Kasauli for confirmation of rabies, where it tested positive for rabies by Fluorescent Antibodies Test and Biological Test. In situations where sensitive parts such as the face are involved, a thorough wound wash with soap and water and application of antiseptics along with immediate PEP may save some lives by not allowing the virus enough time to attach to and infect the nerve cells.
2019 年 1 月 4 日,一名 8 岁女童左侧腮腺区被疑似狂犬病犬咬伤。伤后 17 小时才到蒂罗格镇立医院接受狂犬病暴露后预防(PEP),并接受了完整的 PEP。2019 年 1 月 29 日,该女童再次因发热、行走困难、颈部下垂和上睑下垂到蒂罗格医院就诊。儿科医生在检查时发现了畏光、恐声和恐水症,随后该患者死于心脏骤停。尸检发现面神经在腮腺内端被切开和损伤。朝向大脑的一端肿胀和水肿。整个大脑被提取出来并送往卡索利中央研究所进行狂犬病确认,荧光抗体试验和生物学试验均证实为狂犬病阳性。在面部等敏感部位受伤的情况下,彻底用肥皂和水冲洗伤口,并使用防腐剂,同时立即进行 PEP,可以为患者争取时间,阻止病毒附着并感染神经细胞,从而挽救一些生命。