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Hydroxyurea for children with sickle cell anemia: Prescribe it early and often.

作者信息

Ware Russell E, McGann Patrick T, Quinn Charles T

机构信息

Division of Hematology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Global Health Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio.

出版信息

Pediatr Blood Cancer. 2019 Aug;66(8):e27778. doi: 10.1002/pbc.27778. Epub 2019 Apr 30.

DOI:10.1002/pbc.27778
PMID:31038282
Abstract
摘要

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Hydroxyurea for children with sickle cell anemia: Prescribe it early and often.给镰状细胞贫血患儿使用羟基脲：尽早且频繁给药。
Pediatr Blood Cancer. 2019 Aug;66(8):e27778. doi: 10.1002/pbc.27778. Epub 2019 Apr 30.
2
Hydroxyurea in very young children with sickle cell anemia is not a cure-all.羟基脲对镰状细胞贫血的幼儿并非万灵药。
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Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa.在撒哈拉以南非洲，用羟脲治疗镰状细胞贫血儿童。
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4
Effect of hydroxyurea therapy on resting energy expenditure in children with sickle cell disease.羟基脲疗法对镰状细胞病患儿静息能量消耗的影响。
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Hydroxyurea for sickle-cell anaemia in Africa: mind the gap.非洲镰状细胞贫血的羟基脲治疗：注意差距。
Lancet Glob Health. 2015 Mar;3(3):e124-5. doi: 10.1016/S2214-109X(14)70371-7.
6
Skin and nail changes in children with sickle cell anemia receiving hydroxyurea therapy.接受羟基脲治疗的镰状细胞贫血患儿的皮肤和指甲变化。
J Am Acad Dermatol. 2001 May;44(5):859-61. doi: 10.1067/mjd.2001.113471.
7
Hydroxyurea as secondary prevention for stroke in children with sickle cell anemia.羟基脲作为镰状细胞贫血患儿中风的二级预防措施。
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Hydroxyurea treatment in children with sickle cell anemia in Central America and the Caribbean countries.中美洲和加勒比国家镰状细胞贫血患儿的羟基脲治疗
Pediatr Blood Cancer. 2006 Jul;47(1):111-2. doi: 10.1002/pbc.20823.
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Effect of hydroxyurea in sickle cell anemia: a clinical trial in children and teenagers with severe sickle cell anemia and sickle cell beta-thalassemia.羟基脲对镰状细胞贫血的影响：一项针对重度镰状细胞贫血和镰状细胞β地中海贫血儿童及青少年的临床试验。
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Hydroxyurea therapy: improving the lives of patients with sickle cell disease.羟基脲疗法：改善镰状细胞病患者的生活
Pediatr Nurs. 2006 Nov-Dec;32(6):541-3.

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The modern use of hydroxyurea for children with sickle cell anemia.羟基脲在镰状细胞贫血患儿中的现代应用。
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Clinical Insights into Sickle Cell Disease: A Comprehensive Multicenter Retrospective Analysis of Clinical Characteristics and Outcomes Across Different Age Groups.镰状细胞病的临床见解：不同年龄组临床特征与结局的多中心综合回顾性分析
J Clin Med. 2024 Nov 28;13(23):7224. doi: 10.3390/jcm13237224.
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The Current Role of Hydroxyurea in the Treatment of Sickle Cell Anemia.
羟基脲在镰状细胞贫血治疗中的当前作用
J Clin Med. 2024 Oct 25;13(21):6404. doi: 10.3390/jcm13216404.
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Scalable noninvasive amplicon-based precision sequencing (SNAPseq) for genetic diagnosis and screening of β-thalassemia and sickle cell disease using a next-generation sequencing platform.使用下一代测序平台的可扩展无创扩增子精准测序（SNAPseq）用于β地中海贫血和镰状细胞病的基因诊断与筛查
Front Mol Biosci. 2023 Dec 13;10:1244244. doi: 10.3389/fmolb.2023.1244244. eCollection 2023.
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Evidence-Based Minireview: In young children with severe sickle cell disease, do the benefits of HLA-identical sibling donor HCT outweigh the risks?循证迷你综述：在患有严重镰状细胞病的幼儿中，HLA 匹配同胞供者 HCT 的益处是否超过风险？
Hematology Am Soc Hematol Educ Program. 2021 Dec 10;2021(1):190-195. doi: 10.1182/hematology.2021000322.
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Clinical Utility of the Addition of Molecular Genetic Testing to Newborn Screening for Sickle Cell Anemia.在镰状细胞贫血新生儿筛查中增加分子基因检测的临床应用价值
Front Med (Lausanne). 2021 Nov 10;8:734305. doi: 10.3389/fmed.2021.734305. eCollection 2021.
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Hydroxyurea Use After Transitions of Care Among Young Adults With Sickle Cell Disease and Tennessee Medicaid Insurance.镰状细胞病年轻患者接受医疗过渡后使用羟脲的情况。
JAMA Netw Open. 2021 Oct 1;4(10):e2128971. doi: 10.1001/jamanetworkopen.2021.28971.
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Editing outside the body: Ex vivo gene-modification for β-hemoglobinopathy cellular therapy.体外交错编辑：用于β-地中海贫血症细胞治疗的体外基因修饰。
Mol Ther. 2021 Nov 3;29(11):3163-3178. doi: 10.1016/j.ymthe.2021.10.002. Epub 2021 Oct 8.
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Effects of hydroxyurea on cytotoxicity, inflammation and oxidative stress markers in neutrophils of patients with sickle cell anemia: dose-effect relationship.羟基脲对镰状细胞贫血患者中性粒细胞的细胞毒性、炎症和氧化应激标志物的影响：剂量效应关系。
Hematol Transfus Cell Ther. 2021 Oct-Dec;43(4):468-475. doi: 10.1016/j.htct.2020.07.011. Epub 2020 Sep 30.
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The Relationship between Health Disparities, Psychosocial Functioning and Health Outcomes in Pediatric Hematology-Oncology and Stem Cell Transplant Populations: Recommendations for Clinical Care.儿科血液肿瘤学和干细胞移植人群中的健康差异、心理社会功能与健康结果之间的关系：临床护理建议。
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