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印度尼西亚心血管疾病风险因素的流行情况和估计的 10 年心血管风险评分:SMARThealth 扩展研究。

Cardiovascular disease risk factor prevalence and estimated 10-year cardiovascular risk scores in Indonesia: The SMARThealth Extend study.

机构信息

Division of Neuroscience and Experimental Psychology, University of Manchester, Manchester, United Kingdom.

University of Brawijaya, Malang, Indonesia.

出版信息

PLoS One. 2019 Apr 30;14(4):e0215219. doi: 10.1371/journal.pone.0215219. eCollection 2019.

Abstract

BACKGROUND

The brunt of cardiovascular disease (CVD) burden globally now resides within low- and middle-income countries, including Indonesia. However, little is known regarding cardiovascular health in Indonesia. This study aimed to estimate the prevalence of elevated CVD risk in a specific region of Indonesia.

METHODS

We conducted full household screening for cardiovascular risk factors among adults aged 40 years and older in 8 villages in Malang District, East Java Province, Indonesia, in 2016-2017. 10-year cardiovascular risk scores were calculated based on the World Health Organization/International Society of Hypertension's region-specific charts that use age, sex, blood pressure, diabetes status and smoking behaviour.

RESULTS

Among 22,093 participants, 6,455 (29.2%) had high cardiovascular risk, defined as the presence of coronary heart disease, stroke or other atherosclerotic disease; estimated 10-year CVD risk of ≥ 30%; or estimated 10-year CVD risk between 10% to 29% combined with a systolic blood pressure of > 140 mmHg. The prevalence of high CVD risk was greater in urban (31.6%, CI 30.7-32.5%) than in semi-urban (28.7%, CI 27.3-30.1%) and rural areas (26.2%, CI 25.2-27.2%). Only 11% and 1% of all the respondents with high CVD risk were on blood pressure lowering and statins treatment, respectively.

CONCLUSIONS

High cardiovascular risk is common among Indonesian adults aged ≥40 years, and rates of preventive treatment are low. Population-based and clinical approaches to preventing CVD should be a priority in both urban and rural areas.

摘要

背景

全球心血管疾病(CVD)负担的主要部分现在存在于低收入和中等收入国家,包括印度尼西亚。然而,对于印度尼西亚的心血管健康状况知之甚少。本研究旨在估计印度尼西亚特定地区升高的 CVD 风险的患病率。

方法

我们在 2016-2017 年对印度尼西亚东爪哇省玛琅区 8 个村庄的 40 岁及以上成年人进行了全面的心血管危险因素家庭筛查。根据世界卫生组织/国际高血压学会的特定区域图表,使用年龄、性别、血压、糖尿病状况和吸烟行为计算 10 年心血管风险评分。

结果

在 22093 名参与者中,6455 名(29.2%)患有高心血管风险,定义为存在冠心病、中风或其他动脉粥样硬化性疾病;估计 10 年 CVD 风险≥30%;或估计 10 年 CVD 风险在 10%至 29%之间,同时收缩压>140mmHg。城市(31.6%,CI 30.7-32.5%)的高 CVD 风险患病率高于半城市(28.7%,CI 27.3-30.1%)和农村地区(26.2%,CI 25.2-27.2%)。所有患有高 CVD 风险的受访者中,仅有 11%和 1%分别接受了降压和他汀类药物治疗。

结论

40 岁及以上印度尼西亚成年人的心血管风险较高,预防治疗率较低。基于人群和临床的预防 CVD 方法应该成为城市和农村地区的优先事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99bd/6490907/ab6f0598fa2e/pone.0215219.g001.jpg

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