Olanipekun Oladipo Ayoola, Oguntola Stephen Olawale, Agoke Adekunle Kayode, Oyebanji Adedayo Hakeem, Ogidan Olamide Nelson, Akinmade Akinola, Dave Dhirendrakumar Jayantilal, Akintomide Anthony Olubunmi, Sanusi Michael, Adeleke Kamar Tayo
Department of Medicine, Cardiology Unit, Faculty of Clinical Sciences, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.
Department of Medicine, Nephrology Unit, Faculty of Clinical Sciences, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria.
Pan Afr Med J. 2025 May 18;50:55. doi: 10.11604/pamj.2025.50.55.45726. eCollection 2025.
coronary artery disease (CAD) is a common cardiovascular disease (CVD) and a notable cause of mortality worldwide. Angiographic diagnosis of CAD is not widely available in sub-Saharan Africa. We assessed the pattern and correlates of CAD among patients referred for coronary angiography in Ado-Ekiti, Nigeria.
patients with clinical suspicion of CAD who were referred for coronary angiography at Afe Babalola University Multi-System Hospital (AMSH) from August 2019 to December 2020 were recruited into the study after a written informed consent was obtained. Serum fasting lipids, electrolytes, urea and creatinine and erythrocyte sedimentation rate (ESR) were assessed. All patients had coronary angiography.
forty-six (46) patients were recruited into the study. The mean age among patients who had CAD was 52.12 years (±10.34). There were 15 (32.6%) females in the study population. CAD was confirmed in 18/46 (39.1%) patients. Triple vessel disease (TVD) was seen in 9/18 (50.0%) of patients who had CAD, hence, the most prevalent CAD disease pattern. ESR was significantly prolonged among patients who had CAD compared to patients who did not have CAD on univariate analysis while diabetes mellitus was an independent risk factor for CAD and conferred a greater than 7-fold risk for CAD (aOR: 7.28, 95% CI 1.15-46.16; p = 0.035).
diabetes mellitus was an independent risk factor for CAD. Triple vessel disease was the most common pattern of CAD in our study. ESR was associated with CAD.
冠状动脉疾病（CAD）是一种常见的心血管疾病（CVD），也是全球范围内一个显著的死亡原因。在撒哈拉以南非洲地区，CAD的血管造影诊断并不普遍。我们评估了尼日利亚阿多-埃基蒂因冠状动脉造影而转诊的患者中CAD的模式及其相关因素。
2019年8月至2020年12月期间，在阿费·巴巴洛拉大学多系统医院（AMSH）因临床怀疑CAD而转诊进行冠状动脉造影的患者，在获得书面知情同意后被纳入研究。评估了血清空腹血脂、电解质、尿素、肌酐和红细胞沉降率（ESR）。所有患者均进行了冠状动脉造影。
46名患者被纳入研究。患有CAD的患者平均年龄为52.12岁（±10.34）。研究人群中有15名（32.6%）女性。46名患者中有18名（39.1%）确诊为CAD。在患有CAD的患者中，9/18（50.0%）出现三支血管病变（TVD），因此，这是最常见的CAD疾病模式。单因素分析显示，与未患CAD的患者相比，患CAD的患者ESR显著延长，而糖尿病是CAD的独立危险因素，患CAD的风险增加7倍以上（调整后比值比：7.28，95%置信区间1.15-46.16；p = 0.035）。
糖尿病是CAD的独立危险因素。在我们的研究中，三支血管病变是CAD最常见的模式。ESR与CAD有关。
