Panico A, Serio F, Bagordo F, Grassi T, Idolo A, DE Giorgi M, Guido M, Congedo M, DE Donno A
Department of Biological and Environmental Science and Technology, University of Salento, Lecce, Italy.
Interuniversity Research Centre on Influenza and other transmitted infections (CIRI-IT), Genoa, Italy.
J Prev Med Hyg. 2019 Mar 29;60(1):E50-E57. doi: 10.15167/2421-4248/jpmh2019.60.1.1080. eCollection 2019 Mar.
Cosmetic products contain a wide range of chemicals to which we are exposed every day. The aim of the study was to determine the presence of potential dangerous substances which can cause adverse health effects by examining product labels.
A total of 283 products were collected from various shops in Lecce (Italy) and divided into 3 categories: rinse-off, leave-on and make-up. The label of every product was examined and a list including fragrances, preservatives and other chemicals of concern was created.
Fragrances were present in 52.3% of the examined products, mostly limonene (76.9%) and linalool (64.6%) but also citronellol (34.1%), geraniol (31.5%), coumarin (30%) and hexyl cinnamal (29.2%). Preservatives showed a rate of 60% and the most frequently identified were phenoxyethanol (48.7%), sodium benzoate (35.6%), potassium sorbate (22%), methylparaben (15.2%) and MI/MCI (9.9%). The other chemicals of concern were detected in 58% of products; included PEGs (62.3%), acrylate copolymer (34%), petrolatum (17.2%), polysorbates (14,8%), BHT (14.7%), ethylhextyl methoxycinnamate (13.6%), benzophenone-1 (3.7%), benzophenone-3 (4.9%), BHA (1.6%), cocamide DEA and toluene (1.2%).
The use of many of these substances is allowed within certain limits, due to their toxicity at higher concentrations. Other important aspects should be considered as, for instance, the possibility of long-term effects. On the other hand, other substances may induce several acute adverse side-effects, i.e. contact dermatitis and allergic reactions. For these reasons, an enhancement of the criteria used for cosmetics formulation is required since many chemicals used singularly or combined are potentially unsafe.
化妆品含有多种我们每天都会接触到的化学物质。本研究的目的是通过检查产品标签来确定是否存在可能导致健康不良影响的潜在危险物质。
从意大利莱切的多家商店共收集了283种产品,并分为3类:冲洗型、驻留型和彩妆型。检查了每种产品的标签,并列出了一份包括香料、防腐剂和其他相关化学物质的清单。
在所检查的产品中,52.3%含有香料,主要是柠檬烯(76.9%)和芳樟醇(64.6%),还有香茅醇(34.1%)、香叶醇(31.5%)、香豆素(30%)和己基肉桂醛(29.2%)。防腐剂的含量为60%,最常检测到的是苯氧乙醇(48.7%)、苯甲酸钠(35.6%)、山梨酸钾(22%)、对羟基苯甲酸甲酯(15.2%)和甲基氯异噻唑啉酮/甲基异噻唑啉酮(9.9%)。在58%的产品中检测到了其他相关化学物质;包括聚乙二醇(62.3%)、丙烯酸酯共聚物(34%)、凡士林(17.2%)、聚山梨醇酯(14.8%)、丁基羟基甲苯(14.7%)、甲氧基肉桂酸乙基己酯(13.6%)、二苯甲酮-1(3.7%)、二苯甲酮-3(4.9%)、丁基羟基茴香醚(1.6%)、椰油酰胺DEA和甲苯(1.2%)。
由于这些物质在高浓度时具有毒性,在一定限度内允许使用其中许多物质。还应考虑其他重要方面,例如长期影响的可能性。另一方面,其他物质可能会引发多种急性不良副作用,即接触性皮炎和过敏反应。出于这些原因,需要加强化妆品配方使用的标准,因为许多单独或混合使用的化学物质可能不安全。