Herman Zachary J, Ilyas Asif M
Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA.
Hand (N Y). 2020 Mar;15(2):157-164. doi: 10.1177/1558944719844346. Epub 2019 May 1.
Injuries to digital nerves are common with trauma to the hand, often requiring surgery. Surgical management of these injuries can be performed using several techniques: direct repair (neurorrhaphy), autograft, allograft, and conduit repair. In light of increasing the availability and use of various digital nerve repair techniques, a new systematic review and meta-analysis was undertaken to comparatively review the available evidence to determine any differences in outcomes to better guide treatment in cases with digital nerve gaps. Current literature on sensory outcomes of various digital nerve repair techniques was reviewed using static 2-point discrimination (S2PD), moving 2-point discrimination (M2PD), Semmes-Weinstein monofilament testing (SWMF), and complication rates as outcomes of interest. After inclusion and exclusion criteria were applied, 15 articles were reviewed and 625 nerve repairs were analyzed. The average gap length for allograft repair, autograft repair, and conduit repair was 15.4, 24.7, and 13.4 mm, respectively. For S2PD outcomes, autograft repair was statistically superior to all other forms of repair. Allograft trended higher than neurorrhaphy and conduit repair, but results were not statistically significant. For SWMF outcomes, autograft repair was statistically superior to conduit repair and neurorrhaphy; it was statistically comparable with allograft repair. Allograft performed statistically superior to conduit repair relative to M2PD. Based on the current updated meta-analysis using newer data and techniques, we found that all available techniques have reasonable outcomes. Yet when managing a digital nerve injury with a gap, thereby excluding direct neurorrhaphy, both autograft and allograft performed comparably and were superior to conduit repair.
手指神经损伤在手部创伤中很常见,通常需要手术治疗。这些损伤的手术处理可以采用多种技术:直接修复(神经缝合术)、自体移植、异体移植和导管修复。鉴于各种手指神经修复技术的可用性和使用不断增加,开展了一项新的系统评价和荟萃分析,以比较现有证据,确定结果的差异,从而更好地指导手指神经缺损病例的治疗。使用静态两点辨别觉(S2PD)、动态两点辨别觉(M2PD)、Semmes-Weinstein单丝试验(SWMF)以及并发症发生率作为感兴趣的结果,对各种手指神经修复技术的感觉结果的现有文献进行了综述。应用纳入和排除标准后,对15篇文章进行了综述,并分析了625例神经修复病例。异体移植修复、自体移植修复和导管修复的平均缺损长度分别为15.4、24.7和13.4毫米。对于S2PD结果,自体移植修复在统计学上优于所有其他修复形式。异体移植的结果比神经缝合术和导管修复更高,但结果无统计学意义。对于SWMF结果,自体移植修复在统计学上优于导管修复和神经缝合术;与异体移植修复在统计学上相当。相对于M2PD,异体移植在统计学上优于导管修复。基于使用更新数据和技术的当前更新的荟萃分析,我们发现所有可用技术都有合理的结果。然而,在处理有缺损的手指神经损伤时,因此排除直接神经缝合术,自体移植和异体移植的效果相当,且优于导管修复。