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1
A Multicenter, Prospective, Randomized, Pilot Study of Outcomes for Digital Nerve Repair in the Hand Using Hollow Conduit Compared With Processed Allograft Nerve.一项多中心、前瞻性、随机、试点研究:比较使用空心导管与处理后的同种异体神经修复手部指神经的效果。
Hand (N Y). 2016 Jun;11(2):144-51. doi: 10.1177/1558944715627233. Epub 2016 Feb 17.
2
Prognostic factors in sensory recovery after digital nerve repair.指神经修复后感觉恢复的预后因素
Acta Orthop Traumatol Turc. 2016;50(2):157-61. doi: 10.3944/AOTT.2015.15.0140.
3
Outcomes of short-gap sensory nerve injuries reconstructed with processed nerve allografts from a multicenter registry study.一项多中心登记研究中,使用处理过的同种异体神经移植重建短间隙感觉神经损伤的结果。
J Reconstr Microsurg. 2015 Jun;31(5):384-90. doi: 10.1055/s-0035-1549160. Epub 2015 Apr 20.
4
Is nerve regeneration after reconstruction with collagen nerve conduits terminated after 12 months? the long-term follow-up of two prospective clinical studies.使用胶原神经导管重建后神经再生在12个月后就停止了吗?两项前瞻性临床研究的长期随访
J Reconstr Microsurg. 2014 Oct;30(8):561-8. doi: 10.1055/s-0034-1375237. Epub 2014 Sep 3.
5
Sensory recovery after primary repair of palmar digital nerves using a Revolnerv(®) collagen conduit: a prospective series of 27 cases.使用Revolnerv(®)胶原蛋白导管对掌侧指神经进行一期修复后的感觉恢复:27例前瞻性系列研究。
Chir Main. 2014 Sep;33(4):279-85. doi: 10.1016/j.main.2014.05.002. Epub 2014 Jun 18.
6
Evaluation of emergency nerve grafting for proper palmar digital nerve defects: a retrospective single centre study.急诊神经移植修复手掌指神经缺损的评估:一项回顾性单中心研究
Orthop Traumatol Surg Res. 2014 Oct;100(6):605-10. doi: 10.1016/j.otsr.2014.05.018. Epub 2014 Aug 23.
7
Is there a profit to use the lateral antebrachial cutaneous nerve as a graft source in digital nerve reconstruction?在指神经重建中使用前臂外侧皮神经作为移植源有收益吗?
Microsurgery. 2014 Jul;34(5):367-71. doi: 10.1002/micr.22220. Epub 2014 Jan 16.
8
Prospective clinical study on digital nerve repair with collagen nerve conduits and review of literature.前瞻性临床研究:胶原蛋白神经导管修复指神经的疗效观察及文献复习
J Reconstr Microsurg. 2014 May;30(4):227-34. doi: 10.1055/s-0033-1358788. Epub 2013 Dec 12.
9
Allograft reconstruction for digital nerve loss.同种异体移植修复指神经损伤。
J Hand Surg Am. 2013 Oct;38(10):1965-71. doi: 10.1016/j.jhsa.2013.07.008. Epub 2013 Aug 30.
10
Sensory recovery outcome after digital nerve repair in relation to different reconstructive techniques: meta-analysis and systematic review.不同重建技术下指神经修复后的感觉恢复结果:荟萃分析与系统评价
Plast Surg Int. 2013;2013:704589. doi: 10.1155/2013/704589. Epub 2013 Jul 30.

数字神经修复技术的感觉结果:一项更新的荟萃分析和系统评价

Sensory Outcomes in Digital Nerve Repair Techniques: An Updated Meta-analysis and Systematic Review.

作者信息

Herman Zachary J, Ilyas Asif M

机构信息

Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

Hand (N Y). 2020 Mar;15(2):157-164. doi: 10.1177/1558944719844346. Epub 2019 May 1.

DOI:10.1177/1558944719844346
PMID:31043071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7076611/
Abstract

Injuries to digital nerves are common with trauma to the hand, often requiring surgery. Surgical management of these injuries can be performed using several techniques: direct repair (neurorrhaphy), autograft, allograft, and conduit repair. In light of increasing the availability and use of various digital nerve repair techniques, a new systematic review and meta-analysis was undertaken to comparatively review the available evidence to determine any differences in outcomes to better guide treatment in cases with digital nerve gaps. Current literature on sensory outcomes of various digital nerve repair techniques was reviewed using static 2-point discrimination (S2PD), moving 2-point discrimination (M2PD), Semmes-Weinstein monofilament testing (SWMF), and complication rates as outcomes of interest. After inclusion and exclusion criteria were applied, 15 articles were reviewed and 625 nerve repairs were analyzed. The average gap length for allograft repair, autograft repair, and conduit repair was 15.4, 24.7, and 13.4 mm, respectively. For S2PD outcomes, autograft repair was statistically superior to all other forms of repair. Allograft trended higher than neurorrhaphy and conduit repair, but results were not statistically significant. For SWMF outcomes, autograft repair was statistically superior to conduit repair and neurorrhaphy; it was statistically comparable with allograft repair. Allograft performed statistically superior to conduit repair relative to M2PD. Based on the current updated meta-analysis using newer data and techniques, we found that all available techniques have reasonable outcomes. Yet when managing a digital nerve injury with a gap, thereby excluding direct neurorrhaphy, both autograft and allograft performed comparably and were superior to conduit repair.

摘要

手指神经损伤在手部创伤中很常见,通常需要手术治疗。这些损伤的手术处理可以采用多种技术:直接修复(神经缝合术)、自体移植、异体移植和导管修复。鉴于各种手指神经修复技术的可用性和使用不断增加,开展了一项新的系统评价和荟萃分析,以比较现有证据,确定结果的差异,从而更好地指导手指神经缺损病例的治疗。使用静态两点辨别觉(S2PD)、动态两点辨别觉(M2PD)、Semmes-Weinstein单丝试验(SWMF)以及并发症发生率作为感兴趣的结果,对各种手指神经修复技术的感觉结果的现有文献进行了综述。应用纳入和排除标准后,对15篇文章进行了综述,并分析了625例神经修复病例。异体移植修复、自体移植修复和导管修复的平均缺损长度分别为15.4、24.7和13.4毫米。对于S2PD结果,自体移植修复在统计学上优于所有其他修复形式。异体移植的结果比神经缝合术和导管修复更高,但结果无统计学意义。对于SWMF结果,自体移植修复在统计学上优于导管修复和神经缝合术;与异体移植修复在统计学上相当。相对于M2PD,异体移植在统计学上优于导管修复。基于使用更新数据和技术的当前更新的荟萃分析,我们发现所有可用技术都有合理的结果。然而,在处理有缺损的手指神经损伤时,因此排除直接神经缝合术,自体移植和异体移植的效果相当,且优于导管修复。