Solving Baroreceptor Mystery: Role of PIEZO Ion Channels.
作者信息
Burke Suzanne D, Jordan Jens, Harrison David G, Karumanchi S Ananth
机构信息
Center for Vascular Biology Research and Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Institute of Aerospace Medicine, German Aerospace Center and Department of Aerospace Medicine, University of Cologne, Cologne, Germany.
出版信息
J Am Soc Nephrol. 2019 Jun;30(6):911-913. doi: 10.1681/ASN.2019020160. Epub 2019 May 1.
Abstract
摘要
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本文引用的文献
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Piezo's membrane footprint and its contribution to mechanosensitivity.Piezo 膜的足迹及其对机械敏感性的贡献。
Elife. 2018 Nov 27;7:e41968. doi: 10.7554/eLife.41968.
2
PIEZOs mediate neuronal sensing of blood pressure and the baroreceptor reflex.PIEZOs 介导神经元对血压的感知和压力感受器反射。
Science. 2018 Oct 26;362(6413):464-467. doi: 10.1126/science.aau6324.
3
Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction.PIEZO1和PIEZO2功能障碍的遗传性疾病。
Curr Top Membr. 2017;79:97-134. doi: 10.1016/bs.ctm.2017.01.001. Epub 2017 Feb 28.
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Mechanically Activated Ion Channels.机械激活离子通道
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Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the double-blind, randomized, placebo-controlled rheos pivotal trial.压力反射激活疗法可降低难治性高血压患者的血压：来自双盲、随机、安慰剂对照 rheos 关键性试验的结果。
J Am Coll Cardiol. 2011 Aug 9;58(7):765-73. doi: 10.1016/j.jacc.2011.06.008.
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Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.Piezo1 和 Piezo2 是两种截然不同的机械激活阳离子通道的必需组成部分。
Science. 2010 Oct 1;330(6000):55-60. doi: 10.1126/science.1193270. Epub 2010 Sep 2.
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A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes.一种由覆盖KIAA0233的基因编码的新型膜蛋白在老年斑相关星形胶质细胞中被转录诱导。
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Baroreceptors, baroreceptor unloading, and the long-term control of blood pressure.压力感受器、压力感受器负荷减轻与血压的长期控制。
Am J Physiol Regul Integr Comp Physiol. 2005 Apr;288(4):R819-27. doi: 10.1152/ajpregu.00813.2004.
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A method for eliciting baroreceptor reflexes from the isolated carotid sinus.一种从离体颈动脉窦诱发压力感受器反射的方法。
J Physiol. 1955 May 27;128(2):33-5P.
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The effects of carotid sinus baroreceptor reflexes on pulmonary arterial pressure and pulmonary blood flow in the dog.颈动脉窦压力感受器反射对犬肺动脉压和肺血流量的影响。
J Physiol. 1958 Sep 23;143(2):343-68. doi: 10.1113/jphysiol.1958.sp006064.
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