1 Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
2 Department of Endocrinology, South Campus, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Diab Vasc Dis Res. 2019 Sep;16(5):474-477. doi: 10.1177/1479164119844695. Epub 2019 May 3.
To evaluate the association between spousal diabetes status and the prevalence of diabetic retinopathy in Chinese patients with type 2 diabetes.
A cross-sectional community-based study was performed in 1510 patients with type 2 diabetes in Shanghai, China. Non-mydriatic digital fundus photography was used to detect diabetic retinopathy. Spousal diabetes status was assessed using a standardised interview questionnaire.
The prevalence of diabetic retinopathy was significantly lower in patients who had diabetic spouses, compared with those who did not (20.2% vs 29.1%, ⩽ 0.01). The fully adjusted odds ratio for diabetic retinopathy in those had diabetic spouses was decreased by 36% (odds ratio = 0.64, 95% confidence interval = 0.42-1.00, = 0.048). The negative correlation between spousal diabetes status and diabetic retinopathy was presented in patients with the duration of diabetes ⩾ 10 years, those with HbA1c ⩾ 7% and those not using lipid-lowering drugs (odds ratio = 0.31, 95% confidence interval = 0.13-0.74, = 0.0082; odds ratio = 0.50, 95% confidence interval = 0.27-0.94, = 0.031; odds ratio = 0.58, 95% confidence interval = 0.37-0.92, = 0.021, respectively).
We demonstrated that spousal diabetes was associated with a lower diabetic retinopathy prevalence in Chinese patients with type 2 diabetes.
评估中国 2 型糖尿病患者配偶糖尿病状况与糖尿病视网膜病变患病率之间的关系。
在中国上海，进行了一项基于社区的横断面研究，纳入了 1510 例 2 型糖尿病患者。使用免散瞳数字眼底照相术检测糖尿病视网膜病变。通过标准化的访谈问卷评估配偶的糖尿病状况。
与无糖尿病配偶的患者相比，有糖尿病配偶的患者糖尿病视网膜病变的患病率显著较低（20.2% vs 29.1%， ⩽ 0.01）。有糖尿病配偶的患者发生糖尿病视网膜病变的调整后比值比降低了 36%（比值比=0.64，95%置信区间=0.42-1.00， ⩽ 0.048）。在糖尿病病程 ⩾ 10 年、HbA1c ⩾ 7%以及未使用降脂药物的患者中，配偶的糖尿病状况与糖尿病视网膜病变之间存在负相关（比值比=0.31，95%置信区间=0.13-0.74， ⩽ 0.0082；比值比=0.50，95%置信区间=0.27-0.94， ⩽ 0.031；比值比=0.58，95%置信区间=0.37-0.92， ⩽ 0.021）。
我们发现中国 2 型糖尿病患者的配偶糖尿病与糖尿病视网膜病变患病率较低有关。
