• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Do Sensitive Periods Exist for Exposure to Adversity?

作者信息

Gabard-Durnam Laurel J, McLaughlin Katie A

机构信息

Division of Developmental Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Department of Psychology, Harvard University, Cambridge, Massachusetts.

出版信息

Biol Psychiatry. 2019 May 15;85(10):789-791. doi: 10.1016/j.biopsych.2019.03.975.

DOI:10.1016/j.biopsych.2019.03.975
PMID:31046937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6580180/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/6580180/505d20a043b3/nihms-1028532-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/6580180/505d20a043b3/nihms-1028532-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb73/6580180/505d20a043b3/nihms-1028532-f0001.jpg

相似文献

1
Do Sensitive Periods Exist for Exposure to Adversity?暴露于逆境是否存在敏感期?
Biol Psychiatry. 2019 May 15;85(10):789-791. doi: 10.1016/j.biopsych.2019.03.975.
2
Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children.在敏感时期经历逆境会导致儿童的表观遗传衰老加速。
Psychoneuroendocrinology. 2020 Mar;113:104484. doi: 10.1016/j.psyneuen.2019.104484. Epub 2019 Nov 6.
3
Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study.童年逆境对 DNA 甲基化影响的敏感期:一项前瞻性纵向研究的结果。
Biol Psychiatry. 2019 May 15;85(10):838-849. doi: 10.1016/j.biopsych.2018.12.023. Epub 2019 Jan 21.
4
Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of Parents and Children (ALSPAC) prospective cohort.儿童期逆境发生时间与儿童期和青春期表观遗传模式的关联:来自阿冯纵向研究父母与子女(ALSPAC)前瞻性队列的研究结果。
Lancet Child Adolesc Health. 2023 Aug;7(8):532-543. doi: 10.1016/S2352-4642(23)00127-X. Epub 2023 Jun 14.
5
Examining the epigenetic mechanisms of childhood adversity and sensitive periods: A gene set-based approach.探讨儿童逆境和敏感期的表观遗传机制:基于基因集的方法。
Psychoneuroendocrinology. 2022 Oct;144:105854. doi: 10.1016/j.psyneuen.2022.105854. Epub 2022 Jun 27.
6
What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: recency, accumulation, or sensitive periods?何种生命历程理论模型最能解释童年逆境暴露与精神病理学症状之间的关系:新近性、累积性还是敏感期?
Psychol Med. 2018 Nov;48(15):2562-2572. doi: 10.1017/S0033291718000181. Epub 2018 Feb 26.
7
Adverse childhood experiences, DNA methylation age acceleration, and cortisol in UK children: a prospective population-based cohort study.英国儿童的不良童年经历、DNA 甲基化年龄加速与皮质醇:一项基于人群的前瞻性队列研究。
Clin Epigenetics. 2020 Apr 7;12(1):55. doi: 10.1186/s13148-020-00844-2.
8
Psychosocial adversity and socioeconomic position during childhood and epigenetic age: analysis of two prospective cohort studies.儿童期心理社会逆境和社会经济地位与表观遗传年龄:两项前瞻性队列研究分析。
Hum Mol Genet. 2018 Apr 1;27(7):1301-1308. doi: 10.1093/hmg/ddy036.
9
The role of DNA methylation in the association between childhood adversity and cardiometabolic disease.DNA 甲基化在儿童期逆境与心血管代谢疾病关联中的作用。
Int J Cardiol. 2018 Mar 15;255:168-174. doi: 10.1016/j.ijcard.2017.12.063. Epub 2017 Dec 24.
10
Exposure to childhood adversity and deficits in emotion recognition: results from a large, population-based sample.暴露于儿童逆境和情绪识别缺陷:来自大型人群样本的结果。
J Child Psychol Psychiatry. 2018 Aug;59(8):845-854. doi: 10.1111/jcpp.12881. Epub 2018 Mar 7.

引用本文的文献

1
Hearing and early life adversity: effects of developmental stress on sensory processing.听力与早期生活逆境:发育应激对感觉加工的影响
Neuropsychopharmacology. 2025 Aug 21. doi: 10.1038/s41386-025-02203-2.
2
Early adversity alters brain architecture and increases susceptibility to mental health disorders.早期逆境会改变大脑结构,并增加患心理健康障碍的易感性。
Nat Rev Neurosci. 2025 Jul 24. doi: 10.1038/s41583-025-00948-9.
3
Childhood Maltreatment and Deviations from Normative Brain Structure: Results from 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD.

本文引用的文献

1
Sensitive Periods for the Effect of Childhood Adversity on DNA Methylation: Results From a Prospective, Longitudinal Study.童年逆境对 DNA 甲基化影响的敏感期:一项前瞻性纵向研究的结果。
Biol Psychiatry. 2019 May 15;85(10):838-849. doi: 10.1016/j.biopsych.2018.12.023. Epub 2019 Jan 21.
2
How Early Experience Shapes Human Development: The Case of Psychosocial Deprivation.早期经历如何塑造人类发展:心理社会剥夺的案例。
Neural Plast. 2019 Jan 14;2019:1676285. doi: 10.1155/2019/1676285.
3
Early Experiences of Threat, but Not Deprivation, Are Associated With Accelerated Biological Aging in Children and Adolescents.
童年期虐待与大脑结构偏离正常:来自ENIGMA重性抑郁障碍和ENIGMA创伤后应激障碍研究中3711名个体的结果
bioRxiv. 2025 Jun 8:2025.06.04.657717. doi: 10.1101/2025.06.04.657717.
4
Research Review: Assessment of early-life adversity and trauma - cumulative risk and dimensional approaches.研究综述:早期逆境与创伤的评估——累积风险与维度方法
J Child Psychol Psychiatry. 2025 Apr 10. doi: 10.1111/jcpp.14170.
5
Childhood adversity is associated with longitudinal white matter changes after adulthood trauma.童年逆境与成年期创伤后的白质纵向变化有关。
medRxiv. 2025 Mar 14:2025.03.08.25323425. doi: 10.1101/2025.03.08.25323425.
6
Implicit neural sensitivity for negatively valued social and non-social visual scenes in young adults exposed to childhood adversity.童年逆境暴露的年轻成年人对负面社会和非社会视觉场景的内隐神经敏感性。
Psychol Med. 2025 Feb 11;55:e37. doi: 10.1017/S0033291725000029.
7
Are there sensitive periods for physical activity to influence the development of executive function in children?体育活动影响儿童执行功能发展是否存在敏感期?
J Sport Health Sci. 2024 Nov 28;14:101015. doi: 10.1016/j.jshs.2024.101015.
8
Maternal psychological distress and temperament traits in children from infancy to late childhood.从婴儿期到童年晚期母亲的心理困扰与儿童的气质特征
JCPP Adv. 2024 May 6;4(3):e12242. doi: 10.1002/jcv2.12242. eCollection 2024 Sep.
9
Developmental neuroplasticity and adversity-related risk for psychopathology.发育性神经可塑性与精神病理学的逆境相关风险。
Neuropsychopharmacology. 2024 Nov;50(1):316-317. doi: 10.1038/s41386-024-01950-y.
10
Strengthening through adversity: The hormesis model in developmental psychopathology.在逆境中成长:发展性心理病理学中的兴奋效应模型
Dev Psychopathol. 2024 Dec;36(5):2390-2406. doi: 10.1017/S0954579424000427. Epub 2024 Mar 27.
早期的威胁经历,而不是剥夺,与儿童和青少年的生物衰老加速有关。
Biol Psychiatry. 2019 Feb 1;85(3):268-278. doi: 10.1016/j.biopsych.2018.09.008. Epub 2018 Sep 26.
4
The Neuro-Environmental Loop of Plasticity: A Cross-Species Analysis of Parental Effects on Emotion Circuitry Development Following Typical and Adverse Caregiving.可塑性的神经-环境循环:对典型和不良照料后父母对情绪回路发育影响的跨物种分析
Neuropsychopharmacology. 2016 Jan;41(1):163-76. doi: 10.1038/npp.2015.204. Epub 2015 Jul 21.
5
Childhood adversity and neural development: deprivation and threat as distinct dimensions of early experience.童年逆境与神经发育:剥夺和威胁作为早期经历的不同维度。
Neurosci Biobehav Rev. 2014 Nov;47:578-91. doi: 10.1016/j.neubiorev.2014.10.012.
6
Balancing plasticity/stability across brain development.在大脑发育过程中平衡可塑性/稳定性。
Prog Brain Res. 2013;207:3-34. doi: 10.1016/B978-0-444-63327-9.00001-1.
7
Cumulative risk and child development.累积风险与儿童发展。
Psychol Bull. 2013 Nov;139(6):1342-96. doi: 10.1037/a0031808. Epub 2013 Apr 8.
8
Beyond diathesis stress: differential susceptibility to environmental influences.超越素质压力:对环境影响的不同敏感性。
Psychol Bull. 2009 Nov;135(6):885-908. doi: 10.1037/a0017376.
9
Experience and brain development.经验与大脑发育
Child Dev. 1987 Jun;58(3):539-59.