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在一家欧洲 IFSO 卓越中心(EAC-BS)接受单吻合胃旁路术(OAGB)的儿童和青少年的 5 年随访结果。

A 5-Year Follow-up in Children and Adolescents Undergoing One-Anastomosis Gastric Bypass (OAGB) at a European IFSO Excellence Center (EAC-BS).

机构信息

Centre of Excellence for the Study and Treatment of Obesity and Diabetes, Calle Estacion, No. 12, 1, 47004, Valladolid, Spain.

出版信息

Obes Surg. 2019 Sep;29(9):2739-2744. doi: 10.1007/s11695-019-03908-2.

DOI:10.1007/s11695-019-03908-2
PMID:31049849
Abstract

BACKGROUND

The children and adolescent population with obesity has increased worldwide, both in developing areas and in developed countries. Consequently, the prevalence of morbid obesity among this population has also increased, leading to an exponential growth of bariatric approaches in this population. Many surgeons fear eventual nutritional sequelae after malabsorptive approaches and prefer restrictive or mixed procedures.

METHODS

A retrospective review of all the morbidly obese patients between 13 and 19 years, undergoing a one-anastomosis gastric bypass (OAGB) as bariatric procedure between 2004 and 2012, was performed.

RESULTS

A total of 39 patients were included, 8 males (20.5%) and 31 females (79.5%), with a mean age of 17.8 ± 2 years (range 13-19 years). Mean preoperative weight was 114.3 ± 20.4 kg and mean BMI 42.2 ± 5.9 kg/m. Preoperative comorbidities include only type 2 diabetes mellitus (T2DM) in 7.9% of the patients, hypertension in 10.3%, and dyslipidemia in 23.1%. Five years after surgery, mean BMI was 25.9 ± 5.3 kg/m and total weight loss 32.1 ± 15.7%. Remission rate of T2DM, hypertension and dyslipidemia was 100%. All the patients received multivitamin and vitamin D supplementation. Anemia secondary to iron deficiency occurred in one female, requiring intravenous iron supplementation during 1 year and later on oral supplementation.

CONCLUSIONS

OAGB is a valid alternative for long-term weight loss and remission of comorbidities in childhood and adolescence. No cases of malnutrition or growth disorders were observed.

摘要

背景

肥胖的儿童和青少年人群在全球范围内都有所增加,无论是在发展中地区还是发达国家。因此,该人群中病态肥胖的患病率也有所增加,导致对此类人群的减重手术方法呈指数级增长。许多外科医生担心采用吸收不良方法后会出现最终的营养后遗症,因此更倾向于采用限制或混合手术。

方法

对 2004 年至 2012 年间接受单吻合口胃旁路术(OAGB)作为减重手术的 13 至 19 岁之间病态肥胖患者进行回顾性分析。

结果

共纳入 39 例患者,其中男性 8 例(20.5%),女性 31 例(79.5%),平均年龄为 17.8±2 岁(13-19 岁)。术前平均体重为 114.3±20.4kg,平均 BMI 为 42.2±5.9kg/m。术前合并症仅包括 7.9%的患者有 2 型糖尿病(T2DM),10.3%的患者有高血压,23.1%的患者有血脂异常。术后 5 年,平均 BMI 为 25.9±5.3kg/m,总体重减轻 32.1±15.7%。T2DM、高血压和血脂异常的缓解率为 100%。所有患者均接受了多种维生素和维生素 D 的补充。1 名女性因缺铁性贫血导致贫血,需要静脉补铁 1 年,随后改为口服补铁。

结论

OAGB 是儿童和青少年长期减重和缓解合并症的有效选择。未观察到营养不良或生长障碍病例。

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