Westfälische Wilhelms-Universität, Organisch-Chemisches Institut, Corrensstrasse 40, 48149, Münster, Germany.
Angew Chem Int Ed Engl. 2019 Jul 8;58(28):9561-9564. doi: 10.1002/anie.201904028. Epub 2019 Jun 5.
Two different approaches for the deoxygenative radical borylation of secondary and tertiary alcohols are presented. These transformations either proceed through a metal-free silyl-radical-mediated pathway or utilize visible-light photoredox catalysis. Readily available xanthates or methyl oxalates are used as radical precursors. The reactions show broad substrate scope and high functional-group tolerance, and are conducted under mild and practical conditions.
本文提出了两种不同的方法，用于仲醇和叔醇的脱氧自由基硼化反应。这些转化要么通过无金属硅自由基介导途径进行，要么利用可见光光氧化还原催化。可轻易获得的黄原酸盐或草酸甲酯被用作自由基前体。这些反应具有广泛的底物范围和高官能团容忍性，并且在温和且实际的条件下进行。
