Ali Sher, Salman Muhammad, Din Misbahud, Khan Kachkol, Ahmad Munib, Khan Faisal Hayat, Arif Muhammad
Department of Biotechnology, Abdul Wali University , Mardan , Pakistan.
Universidade Federal do Paraná Brazil, Department of Chemistry , Parana , Brazil.
Pol J Microbiol. 2019;68(1):115-119. doi: 10.21307/pjm-2019-013.
The current study is a retrospective epidemic report regarding dengue fever (DF) virus infection cases (2017) from fifteen districts of KPK, Pakistan. Medical records of 120 948 patients were reviewed retrospectively for demographic, clinical and laboratory data. The presence of dengue infection was confirmed by NS1-ELISA and RT-PCR, respectively. The total positive cases (of suspected DF samples) were 24 938 (20.6%), whereas seventy cases (0.28%) had a fatal outcome. Mean age ± SD of the dengue patients was 26 ± 19.8 years, while; the most affected age group was from 16 to 30 years (Chi-square: 12 820.125, p: 0.00). The infected males were 65.3%, and that of the female was 34.7%. All the dengue-infected patients were observed with symptoms of severe fever (100%), body aches (95%), gums and nose bleeding (5%), skin rashes (30%), vomiting (70%). The highest infection rate was found in district Peshawar and that of the lowest was in Bannu, Hungu and Luki Marwat. A high rate of dengue infection was found in post-monsoon months i.e. October (41%) and September (32%) of the year. The results proved that if the dengue outbreaks reveal further in KPK, it could alarmingly increase the mortality rate. Therefore, the Department of Public Health in KPK, Pakistan may take proper measures to avoid and control dengue epidemics in the future. The current study is a retrospective epidemic report regarding dengue fever (DF) virus infection cases (2017) from fifteen districts of KPK, Pakistan. Medical records of 120 948 patients were reviewed retrospectively for demographic, clinical and laboratory data. The presence of dengue infection was confirmed by NS1-ELISA and RT-PCR, respectively. The total positive cases (of suspected DF samples) were 24 938 (20.6%), whereas seventy cases (0.28%) had a fatal outcome. Mean age ± SD of the dengue patients was 26 ± 19.8 years, while; the most affected age group was from 16 to 30 years (Chi-square: 12 820.125, p: 0.00). The infected males were 65.3%, and that of the female was 34.7%. All the dengue-infected patients were observed with symptoms of severe fever (100%), body aches (95%), gums and nose bleeding (5%), skin rashes (30%), vomiting (70%). The highest infection rate was found in district Peshawar and that of the lowest was in Bannu, Hungu and Luki Marwat. A high rate of dengue infection was found in post-monsoon months i.e. October (41%) and September (32%) of the year. The results proved that if the dengue outbreaks reveal further in KPK, it could alarmingly increase the mortality rate. Therefore, the Department of Public Health in KPK, Pakistan may take proper measures to avoid and control dengue epidemics in the future.
本研究是一项关于巴基斯坦开伯尔-普赫图赫瓦省(KPK)15个地区登革热(DF)病毒感染病例(2017年)的回顾性疫情报告。对120948例患者的病历进行回顾性分析,以获取人口统计学、临床和实验室数据。分别通过NS1-ELISA和RT-PCR确认登革热感染的存在。(疑似登革热样本中的)总阳性病例为24938例(20.6%),而70例(0.28%)有致命结局。登革热患者的平均年龄±标准差为26±19.8岁,其中受影响最严重的年龄组为16至30岁(卡方值:12820.125,p值:0.00)。感染男性占65.3%,女性占34.7%。所有登革热感染患者均出现严重发热(100%)、身体疼痛(95%)牙龈和鼻出血(5%)、皮疹(30%)、呕吐(70%)等症状。白沙瓦地区的感染率最高,而班努、洪古和卢基马尔瓦特地区的感染率最低。在季风后月份,即该年的10月(41%)和9月(32%)发现登革热感染率较高。结果证明,如果登革热疫情在开伯尔-普赫图赫瓦省进一步爆发,可能会惊人地提高死亡率。因此,巴基斯坦开伯尔-普赫图赫瓦省公共卫生部可能需要采取适当措施,以避免和控制未来的登革热疫情。本研究是一项关于巴基斯坦开伯尔-普赫图赫瓦省(KPK)15个地区登革热(DF)病毒感染病例(2017年)的回顾性疫情报告。对1209块8例患者的病历进行回顾性分析,以获取人口统计学、临床和实验室数据。分别通过NS1-ELISA和RT-PCR确认登革热感染的存在。(疑似登革热样本中的)总阳性病例为24938例(20.6%),而70例(0.28%)有致命结局。登革热患者的平均年龄±标准差为26±19.8岁,其中受影响最严重的年龄组为16至30岁(卡方值:12820.125,p值:0.00)。感染男性占65.3%,女性占34.7%。所有登革热感染患者均出现严重发热(100%)、身体疼痛(95%)牙龈和鼻出血(5%)、皮疹(30%)、呕吐(70%)等症状。白沙瓦地区的感染率最高,而班努、洪古和卢基马尔瓦特地区的感染率最低。在季风后月份,即该年的10月(4%)和9月(32%)发现登革热感染率较高。结果证明,如果登革热疫情在开伯尔-普赫图赫瓦省进一步爆发,可能会惊人地提高死亡率。因此,巴基斯坦开伯尔-普赫图赫瓦省公共卫生部可能需要采取适当措施,以避免和控制未来的登革热疫情。