Junge J, Horn T, Christoffersen P
Virchows Arch A Pathol Anat Histopathol. 1987;410(6):553-8. doi: 10.1007/BF00781692.
One hundred and five biopsies with centrilobular and/or portal/periportal fibrosis of different aetiology were examined by light microscopy for the presence of megamitochondria (MM). Sixty eight patients had some daily alcohol intake, 37 did not. The incidence of MM in the group with daily alcohol consumption was 49% and in the group without only 5%. Two types of MM were identified. Type I MM (round to oval) were located mainly in zone 3 and type II (needle-shaped) mainly in zone 1. Both types were related to alcoholic liver disease.
对105例因不同病因导致小叶中心和/或门静脉/门静脉周围纤维化的活检组织进行光学显微镜检查，以确定是否存在巨型线粒体（MM）。68例患者有日常饮酒习惯，37例没有。每日饮酒组中MM的发生率为49%，无饮酒习惯组仅为5%。鉴定出两种类型的MM。I型MM（圆形至椭圆形）主要位于3区，II型（针状）主要位于1区。两种类型均与酒精性肝病有关。
