Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada; Population Oncology, BC Cancer, Vancouver, Canada.
Population Oncology, BC Cancer, Vancouver, Canada; Community Health Sciences, University of Manitoba, Winnipeg, Canada.
Cancer Epidemiol. 2019 Jun;60:174-178. doi: 10.1016/j.canep.2019.04.010. Epub 2019 May 1.
Breast cancer rates vary internationally and between immigrant and non-immigrant populations. We describe breast cancer incidence by birth region and country in British Columbia, Canada.
We linked population-based health and immigration databases for a population with >1.29 million immigrants to assess breast cancer incidence among immigrant and non-immigrant women. We report age-standardized incidence ratios (SIRs) by birth region and country using non-immigrant women as the standard.
SIRs varied widely by both birth country and region. Low rates were found for South (SIR = 0.52, 95% CI: 0.47,0.59) and East Asian (SIR = 0.75, 95% CI: 0.72,0.79) women and a higher rate for Western Europeans (SIR = 1.15, 95% CI: 1.01,1.30).
There is considerable variation in SIRs across some of British Columbia's largest immigrant populations and several demonstrate significantly different risk profiles compared to non-immigrants. These findings provide unique data to support breast cancer prevention and control.
乳腺癌的发病率在国际上以及移民和非移民人群之间存在差异。我们描述了加拿大不列颠哥伦比亚省按出生地区和国家划分的乳腺癌发病率。
我们将基于人群的健康和移民数据库进行了关联，以评估移民和非移民妇女的乳腺癌发病率。我们报告了按出生地区和国家划分的年龄标准化发病率比（SIR），并以非移民妇女为标准。
出生国和地区的 SIR 差异很大。南部（SIR=0.52，95%CI：0.47,0.59）和东亚（SIR=0.75，95%CI：0.72,0.79）女性的发病率较低，而西欧人（SIR=1.15，95%CI：1.01,1.30）的发病率较高。
不列颠哥伦比亚省一些最大的移民群体的 SIR 存在相当大的差异，其中一些与非移民相比显示出明显不同的风险特征。这些发现为乳腺癌的预防和控制提供了独特的数据支持。
