Cardio-Oncology Service, Department of Cardiology, Barts Heart Centre, Barts Health NHS Trust, St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK.
Department of Cardiology, Barts NHS Health Trust, Royal London Hospital, Whitechapel Road, London, E1 1BB, UK.
Curr Treat Options Oncol. 2019 May 6;20(6):46. doi: 10.1007/s11864-019-0644-3.
Coronary artery disease (CAD) and cancer often occur in the same patients via common biological pathways and shared risk factors. A variety of chemotherapeutic agents and radiotherapy can influence the development and progression of CAD. The diagnosis of ischaemic heart disease may be challenging in certain cases such as premature CAD secondary to radiotherapy. The management of CAD in cancer patients in the stable, acute and chronic settings can often be complicated by issues related to ongoing or previous cancer treatment or the cancer itself. A multidisciplinary approach in the setting of a cardio-oncology service is often best-served to optimally treat such patients.
冠状动脉疾病（CAD）和癌症常通过共同的生物学途径和共同的危险因素发生在同一患者身上。各种化疗药物和放射治疗会影响 CAD 的发生和发展。在某些情况下，如因放射治疗导致的早发性 CAD，缺血性心脏病的诊断可能具有挑战性。在稳定期、急性期和慢性期的癌症患者中，CAD 的管理往往会因正在进行或之前的癌症治疗或癌症本身相关的问题而变得复杂。在心脏肿瘤服务中心，多学科方法通常是为这些患者提供最佳治疗的最佳方法。
