收缩压和舒张压作为挪威中年男性冠心病的预测指标。
Systolic and diastolic blood pressures as predictors of coronary heart disease in middle aged Norwegian men.
作者信息
Tverdal A
出版信息
Br Med J (Clin Res Ed). 1987 Mar 14;294(6573):671-3. doi: 10.1136/bmj.294.6573.671.
Abstract
Systolic and diastolic blood pressures were compared as predictors of mortality from coronary heart disease in Norwegian men aged 35-49. A total of 39,207 men were followed up for an average of 8.9 years; 385 died of coronary heart disease. Diastolic blood pressure seemed to be the better predictor, the difference being most pronounced in the age group 35-39. At this age 26% more deaths from coronary heart disease were found in the upper quintile of diastolic blood pressure compared with the upper quintile of systolic blood pressure. At ages 45-49 there were almost the same numbers of deaths from coronary heart disease in the upper quintiles of systolic and diastolic pressures. These findings suggest that the relative predictive strength of systolic and diastolic blood pressure may be dependent on age. Furthermore, for very obese men the association between blood pressure and death from coronary heart disease is much weaker.
摘要
对挪威35至49岁男性的收缩压和舒张压作为冠心病死亡率预测指标进行了比较。共有39207名男性接受了平均8.9年的随访；385人死于冠心病。舒张压似乎是更好的预测指标，这一差异在35至39岁年龄组最为明显。在这个年龄段，舒张压最高五分位数人群中冠心病死亡人数比收缩压最高五分位数人群多26%。在45至49岁年龄段，收缩压和舒张压最高五分位数人群中冠心病死亡人数几乎相同。这些发现表明，收缩压和舒张压的相对预测强度可能取决于年龄。此外，对于极度肥胖的男性，血压与冠心病死亡之间的关联要弱得多。
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