Faculty of Chinese Medicine, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Avenida Wai Long, Taipa, Macao SAR, China.
Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Avenida da Universidade, Taipa, Macao SAR, China.
Curr Vasc Pharmacol. 2020;18(4):322-333. doi: 10.2174/1570161117666190507112157.
Aging has become a worldwide problem. During this process, the incidence of related diseases such as diabetes and atherosclerosis increases dramatically. Studies within the most recent two decades suggest a pivotal role of Advanced Glycation End Products (AGEs) in the aging process. This review aims to systemically summarize the effects and potential mechanism of Chinese Medicines on inhibiting AGEs-related aging diseases.
衰老是一个全球性的问题。在此过程中,糖尿病和动脉粥样硬化等相关疾病的发病率显著增加。最近二十年的研究表明,晚期糖基化终产物(AGEs)在衰老过程中起着关键作用。本综述旨在系统总结中药抑制 AGEs 相关衰老疾病的作用及潜在机制。