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Cross-reactive monoclonal antibodies to alcohol dehydrogenases.

作者信息

Talbot B G, Bilodeau G

出版信息

Experientia. 1987 Apr 15;43(4):426-8. doi: 10.1007/BF01940438.

DOI:10.1007/BF01940438
PMID:3106080
Abstract

Three anti-horse liver alcohol dehydrogenase (HLADH) monoclonal antibodies are described. Two are specific for ADH and cross-react with class I and II enzymes from mouse, horse and Chinese hamster. They are specific for the native enzyme but do not inhibit enzyme activity except when combined at high concentration. The third antibody was isolated as a response to rabbit metallothionein. It binds metalloproteins and inhibits ADH activity.

摘要

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本文引用的文献

1
Purification and properties of two distinct groups of ADH isozymes from Chinese hamster liver.中国仓鼠肝脏中两种不同类型乙醇脱氢酶同工酶的纯化及性质
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人类乙醇脱氢酶chi-ADH同工酶的免疫学和生物化学特性
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