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Moving miRNAs to therapeutic targets in colorectal cancer.

作者信息

McGregor Mark, Price Timothy J

机构信息

Department of Medical Oncology, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville 5011, Australia.

Department of Medical Oncology, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville 5011, Australia; University of Adelaide, School of Medicine, North Terrace, Adelaide 5000, Australia.

出版信息

EBioMedicine. 2019 May;43:13-14. doi: 10.1016/j.ebiom.2019.04.051. Epub 2019 May 3.

DOI:10.1016/j.ebiom.2019.04.051
PMID:31060899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6558254/
Abstract
摘要

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本文引用的文献

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MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway.miR-338-5p 通过抑制磷脂酰肌醇 3-激酶、催化亚基 3 介导的自噬通路促进结直肠癌的转移。
EBioMedicine. 2019 May;43:270-281. doi: 10.1016/j.ebiom.2019.04.010. Epub 2019 Apr 12.
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Circulating miR-338-5p is a potential diagnostic biomarker in colorectal cancer.循环 miR-338-5p 是结直肠癌的潜在诊断生物标志物。
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Autophagy in cancer: a complex relationship.自噬与肿瘤：一种复杂的关系。
Biochem J. 2018 Jun 11;475(11):1939-1954. doi: 10.1042/BCJ20170847.
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miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts.微小RNA-31通过抑制癌症相关成纤维细胞中的自噬来影响结肠直肠癌细胞。
Oncotarget. 2016 Nov 29;7(48):79617-79628. doi: 10.18632/oncotarget.12873.
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Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1.维替泊芬的肿瘤选择性蛋白毒性独立于YAP1抑制结肠癌进展。
Sci Signal. 2015 Oct 6;8(397):ra98. doi: 10.1126/scisignal.aac5418.
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Combined MTOR and autophagy inhibition: phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma.联合抑制哺乳动物雷帕霉素靶蛋白（mTOR）和自噬：羟氯喹和替西罗莫司治疗晚期实体瘤和黑色素瘤患者的I期试验
Autophagy. 2014 Aug;10(8):1391-402. doi: 10.4161/auto.29119. Epub 2014 May 20.
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Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer.三重 microRNA 分类器的潜力：miR-193a-3p、miR-23a 和 miR-338-5p 用于早期检测结直肠癌。
BMC Cancer. 2013 Jun 8;13:280. doi: 10.1186/1471-2407-13-280.
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Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells.氯喹增强氟尿嘧啶对结肠癌细胞的抗癌作用。
BMC Cancer. 2010 Jul 15;10:370. doi: 10.1186/1471-2407-10-370.
9
Inhibition of PI3k class III-dependent autophagy prevents apoptosis and necrosis by oxidative stress in dopaminergic neuroblastoma cells.PI3K Ⅲ类依赖性自噬抑制通过氧化应激防止多巴胺能神经母细胞瘤细胞的凋亡和坏死。
Toxicol Sci. 2010 Sep;117(1):152-62. doi: 10.1093/toxsci/kfq170. Epub 2010 Jun 4.
10
Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901.I类磷脂酰肌醇3激酶抑制剂LY294002通过p53途径激活胃癌细胞系SGC7901中的自噬并诱导凋亡。
Acta Biochim Biophys Sin (Shanghai). 2008 Mar;40(3):194-201. doi: 10.1111/j.1745-7270.2008.00393.x.