Söderström K O
Int J Gynecol Pathol. 1987;6(1):55-65. doi: 10.1097/00004347-198703000-00007.
The binding of fluorescein isothiocyanate conjugated concanavalin A (Con A), Triticum vulgaris (WGA), Glycine maximum (SBA), dolichos biflorus (DBA), Ulex europaeus (UEA), Arachis hypogaea (PNA), and Ricinus communis (RCA) to human proliferative, secretory, and atrophic endometrium was studied. The binding of Con A and WGA increased markedly during the progression of the endometrium from the proliferative to the secretory phase. Triticum vulgaris seemed to bind to the secretion and was transported from the glandular cells to the glandular lumen during the secretory phase. Glycine maximum bound to the surface epithelium but not to the glandular cells. Some of the stromal cells showed binding with various lectins that also partly followed the endometrial cycle. The binding of the lectins in formalin-fixed paraffin sections as compared with that in frozen sections showed only slight differences that were restricted to SBA and DBA. The changes in the lectin binding of the endometrium reflect morphological and functional changes and lectin staining might possibly be used in further studies relating to functional disturbances of the endometrium.
研究了异硫氰酸荧光素偶联的伴刀豆球蛋白A（Con A）、小麦胚凝集素（WGA）、大豆凝集素（SBA）、双花扁豆凝集素（DBA）、荆豆凝集素（UEA）、花生凝集素（PNA）和蓖麻凝集素（RCA）与人增殖期、分泌期和萎缩期子宫内膜的结合情况。在子宫内膜从增殖期向分泌期进展过程中，Con A和WGA的结合显著增加。小麦胚凝集素似乎与分泌物结合，并在分泌期从腺细胞转运至腺腔。大豆凝集素与表面上皮结合，但不与腺细胞结合。一些基质细胞显示出与各种凝集素的结合，这种结合也部分遵循子宫内膜周期。与冰冻切片相比，福尔马林固定石蜡切片中凝集素的结合仅显示出微小差异，且仅限于SBA和DBA。子宫内膜凝集素结合的变化反映了形态和功能的变化，凝集素染色可能可用于与子宫内膜功能紊乱相关的进一步研究。
