临床非黏液型铜绿假单胞菌菌株产生藻酸盐的情况。
Alginate production by clinical nonmucoid Pseudomonas aeruginosa strains.
作者信息
Anastassiou E D, Mintzas A C, Kounavis C, Dimitracopoulos G
出版信息
J Clin Microbiol. 1987 Apr;25(4):656-9. doi: 10.1128/jcm.25.4.656-659.1987.
Abstract
The slime material from a revertant nonmucoid variant, derived by serial passage of a heavily mucoid Pseudomonas aeruginosa strain isolated from a patient with bacteremia, was found to contain 16% uronic acids, 48.5% carbohydrates, 11% protein, and 2% lipids. Chromatographic analysis by ion exchange chromatography revealed that this extracellular material consisted of three fractions, one uronic acid fraction with properties similar to those of the alginate fraction of the parental strain and two other fractions consisting of neutral sugars and proteins in approximately a 5:1 ratio. In addition, the slime material from six other clinical macroscopic nonmucoid P. aeruginosa strains was found to contain alginate. These results demonstrate that alginate production in various amounts is a property shared by all P. aeruginosa strains.
摘要
从一名菌血症患者分离出的高度黏液型铜绿假单胞菌菌株经连续传代获得的回复非黏液型变体的黏液物质，被发现含有16%的糖醛酸、48.5%的碳水化合物、11%的蛋白质和2%的脂质。离子交换色谱法的色谱分析表明，这种细胞外物质由三个部分组成，一个糖醛酸部分，其性质与亲本菌株的藻酸盐部分相似，另外两个部分由中性糖和蛋白质组成，比例约为5:1。此外，还发现来自其他六种临床宏观非黏液型铜绿假单胞菌菌株的黏液物质含有藻酸盐。这些结果表明，不同数量的藻酸盐产生是所有铜绿假单胞菌菌株共有的特性。
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