Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
United European Gastroenterol J. 2019 May;7(4):548-556. doi: 10.1177/2050640619836052. Epub 2019 Mar 5.
Esophageal food impaction is relatively common and increasing over time. Treatment ranges from medications to invasive endoscopic therapies. The endoscopic push technique has been advised against in favor of endoscopic retrieval for safety concerns. We sought to assess use patterns and safety of treatments for food impaction in a population-based retrospective review.
A database of recorded esophageal food impactions in Olmsted County, MN, USA, from 1975-2011 was reviewed for patient demographics, treatment, and complications.
A total of 645 impactions occurred, with increasing incidence over time, peaking at 23.2 per year (2000-2004). Medications (almost exclusively glucagon) were successful in relieving impactions 34.5% of the time when trialed. Urgent endoscopy was common (74.0%), as was the need for endoscopic therapy (67.1%). Endoscopic therapy increased over time, with the endoscopic push technique becoming most common. Esophageal complications (deep mucosal injury or perforation) increased over time but remained rare (peak 11%). There was no difference in complications between push and retrieval techniques.
The endoscopic push technique is safe in comparison to endoscopic retrieval in esophageal food impactions. While complications surrounding impaction have increased, they remain rare. Medication trials are reasonable, as long as they do not delay endoscopy, and may prevent the need for emergent endoscopy in one-third of cases.
食管食物嵌塞较为常见,且随着时间的推移呈上升趋势。治疗方法从药物治疗到侵入性内镜治疗都有。出于安全考虑,不建议使用内镜推送技术,而推荐使用内镜取出技术。我们旨在通过基于人群的回顾性研究来评估治疗食管食物嵌塞的治疗方法的使用模式和安全性。
我们对美国明尼苏达州奥姆斯特德县(Olmsted County)1975 年至 2011 年期间记录的食管食物嵌塞的数据库进行了回顾,以评估患者的人口统计学资料、治疗方法和并发症。
共发生 645 例嵌塞,发病率随时间推移而增加,在 2000-2004 年达到高峰,每年 23.2 例。尝试使用药物(几乎全部为胰高血糖素)缓解嵌塞的成功率为 34.5%。紧急内镜检查较为常见(74.0%),内镜治疗也很常见(67.1%)。内镜治疗的方法随时间推移而增加,内镜推送技术变得越来越普遍。食管并发症(深层黏膜损伤或穿孔)随时间推移而增加,但仍很少见(高峰 11%)。推送和取出技术之间的并发症没有差异。
与内镜取出技术相比,食管食物嵌塞的内镜推送技术是安全的。尽管与嵌塞相关的并发症有所增加,但仍很少见。药物试验是合理的,只要它们不延迟内镜检查,就可以预防三分之一的紧急内镜检查的需要。