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输精管切除术的免疫学后果：I. 输精管切除术后一年的前瞻性研究。

Immunological consequences of vasectomy: I. Prospective study through one-year postvasecotomy.

作者信息

Lucas P L, Rose N R

出版信息

Arch Androl. 1978 May;1(3):249-55. doi: 10.3109/01485017808988344.

DOI:10.3109/01485017808988344
PMID:310663
Abstract

Autoimmunity to sperm developed in two-thirds of men within 1 year after vasectomy as measured by sperm agglutinating and sperm immobilizing antibody tests. Sperm antibody responses to vasectomy were greater in younger than in older men. A direct relationship was apparent between increasing incidence of sperm immobilizing antibody and genetic predisposition to autoimmune disease. Some vasectomized men developed immune responses to autoantigens other than spermatozoa. Increased antithyroglobulin activity was evenly divided between patients who formed sperm antibody and those who did not. Antinuclear activity was more frequent in patients who were sperm antibody responders.

摘要

通过精子凝集和精子制动抗体检测发现，三分之二的男性在输精管结扎术后1年内会产生精子自身免疫。年轻男性对输精管结扎术的精子抗体反应比年长男性更强烈。精子制动抗体发病率的增加与自身免疫性疾病的遗传易感性之间存在明显的直接关系。一些输精管结扎的男性对精子以外的自身抗原产生了免疫反应。形成精子抗体的患者和未形成精子抗体的患者中抗甲状腺球蛋白活性增加的情况分布均匀。精子抗体反应阳性的患者中抗核活性更为常见。

相似文献

1
Immunological consequences of vasectomy: I. Prospective study through one-year postvasecotomy.输精管切除术的免疫学后果：I. 输精管切除术后一年的前瞻性研究。
Arch Androl. 1978 May;1(3):249-55. doi: 10.3109/01485017808988344.
2
The immune response to vasectomy and its relation to the HLA system.输精管切除术的免疫反应及其与HLA系统的关系。
Tissue Antigens. 1979 Aug;14(2):115-39. doi: 10.1111/j.1399-0039.1979.tb00830.x.
3
Immunological and clinical consequences of vasectomy.输精管切除术的免疫学及临床后果
Andrologia. 1982 Jan-Feb;14(1):15-22. doi: 10.1111/j.1439-0272.1982.tb03089.x.
4
Immunological consequences of vasectomy.输精管切除术的免疫学后果。
Arch Androl. 1981 Sep;7(2):193-9. doi: 10.3109/01485018108999307.
5
Immunological effects of vasectomy.输精管切除术的免疫效应
J Urol. 1982 Jun;127(6):1063-6. doi: 10.1016/s0022-5347(17)54228-7.
6
Lack of association of the development of anti-sperm antibodies and other autoantibodies as a consequence of vasectomy.输精管结扎术后抗精子抗体及其他自身抗体产生之间不存在关联。
Int J Fertil. 1977;22(2):104-9.
7
Autoantibodies against spermatozoal antigens detected by immunoblotting and agglutination. A longitudinal study of vasectomized males.通过免疫印迹法和凝集反应检测到的抗精子抗原自身抗体。对输精管结扎男性的纵向研究。
J Reprod Immunol. 1987 Jan;10(1):15-26. doi: 10.1016/0165-0378(87)90046-5.
8
Vasectomy, serum assays, and coronary heart disease symptoms and risk factors.输精管切除术、血清检测以及冠心病症状和风险因素。
J Clin Epidemiol. 1993 Jan;46(1):101-9. doi: 10.1016/0895-4356(93)90014-r.
9
Immunological consequences of vasectomy: a review.输精管结扎术的免疫学后果：综述
Ann Immunol. 1978;129C(2-3):301-22.
10
Autoimmunity to sperm antigens in vasectomized men.输精管切除术后男性对精子抗原的自身免疫反应。
Clin Exp Immunol. 1975 Jul;21(1):65-74.

引用本文的文献

1
Should We Still be Performing Vasectomies?是否还应该施行输精管切除术？
Can Fam Physician. 1981 Dec;27:1959-61.
2
High titres of serum antinuclear antibodies, mostly directed against nucleolar antigens, are associated with the presence of coronary atherosclerosis.高滴度的血清抗核抗体，大多针对核仁抗原，与冠状动脉粥样硬化的存在有关。
Ann Rheum Dis. 2002 Feb;61(2):110-4. doi: 10.1136/ard.61.2.110.