Deakin University, Australia.
Murdoch Children's Research Institute, Australia.
Autism. 2020 Jan;24(1):26-40. doi: 10.1177/1362361319844636. Epub 2019 May 9.
Parents of children with autism spectrum disorder appear to experience high levels of psychological distress, yet little is known about the prevalence of psychological disorders in this population. The aim of this systematic review and meta-analysis was to estimate the proportion of these parents who experience clinically significant psychopathology. Articles reporting proportions of psychological disorders in a sample of parents of children with autism spectrum disorder were located. The initial search returned 25,988 articles. Thirty-one studies with a total sample of 9208 parents were included in the final review. The median meta-analytic proportions were 31% (95% confidence interval = [24%, 38%]) for depressive disorders, 33% (95% confidence interval = [20%, 48%]) for anxiety disorders, 10% (95% confidence interval = [1%, 41%]) for obsessive-compulsive disorder, 4% (95% confidence interval = [0%, 22%]) for personality disorders, 2% (95% confidence interval = [1%, 4%]) for alcohol and substance use disorders and 1% (95% confidence interval = [0%, 5%]) for schizophrenia spectrum disorders. Significant heterogeneity was detected in these categories. Further research is needed to gain more insight into variables that may moderate parental psychopathology. This review and meta-analysis is the first to provide prevalence estimates of psychological disorders in parents of children with autism spectrum disorder.
自闭症谱系障碍儿童的父母似乎经历着高水平的心理困扰，但人们对这一人群中心理障碍的患病率知之甚少。本系统评价和荟萃分析的目的是估计这些父母经历临床显著精神病理学的比例。本文报道了自闭症谱系障碍儿童父母样本中心理障碍的比例。最初的搜索返回了 25988 篇文章。最终的综述共纳入了 31 项研究，共有 9208 名父母作为样本。荟萃分析的中位数比例分别为：抑郁障碍 31%（95%置信区间 [24%，38%]）、焦虑障碍 33%（95%置信区间 [20%，48%]）、强迫症 10%（95%置信区间 [1%，41%]）、人格障碍 4%（95%置信区间 [0%，22%]）、酒精和物质使用障碍 2%（95%置信区间 [1%，4%]）以及精神分裂症谱系障碍 1%（95%置信区间 [0%，5%]）。这些类别中存在显著的异质性。需要进一步的研究来更深入地了解可能调节父母精神病理学的变量。本综述和荟萃分析首次提供了自闭症谱系障碍儿童父母心理障碍的患病率估计。
